Rat IL-18 ELISA Kit检测试剂盒(酶联免疫吸附法)
¥1,600.00 – ¥2,650.00
在售SKU:70-EK318-48, 70-EK318-96, EK318, il-18
- 分子靶点:IL18
- 种属:大鼠
- 样本类型:血清、血浆样本
- 检测样本体积:血清、血浆样本10μL
- 灵敏度:1.81pg/mL
- 检测范围:15.63-1000pg/mL
- 回收率:86%-119%
ELISA试剂盒详细信息
商品名 | Rat IL-18 酶联免疫检测试剂盒 |
---|---|
种属 | 大鼠 |
靶点 | IL18 |
检测方法 | 双抗体夹心法 |
检测样本类型 | 血清、血浆样本 |
检测样本体积 | 血清、血浆样本10μL |
灵敏度 | 1.81pg/mL |
线性范围 | 15.63-1000pg/mL |
精密度 | 板内变异系数:3.21%-6.34%;板间变异系数:2.6-5.12% |
回收率 | 86%-119% |
平均回收率 | 100% |
板式 | |
保存条件 | 2-8℃保存。已拆开:标准品-20℃保存,其它4℃。 |
运输条件 | 2-8℃冰袋运输 |
检测原理 | 本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后,加入显色底物(TMB),避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应,在450nm波长(参考波长570 - 630nm)测定吸光度值。 |
分子信息
IL18 分子靶点信息概述
- 分子名:IL18, interleukin 18
- 基因家族:Interleukins
- 别名:IGIF; IL1F4; IL-1g; IL-18
- 全称:interferon-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor)
IL18 分子靶点综述
白细胞介素18(IL-18),又名干扰素γ诱导因子,是一种促炎性细胞因子,在人类中由IL18基因编码。IL-18属于IL-1超家族,由巨噬细胞和其它细胞分泌产生。IL-18刺激后,自然杀伤细胞(NK)和某些T细胞就会释放另一种重要的细胞因子—干扰素γ或Ⅱ型干扰素,进而激活巨噬细胞或其它细胞。IL-18可诱导产生严重的炎症反应,同样可增加人类神经元中β-淀粉样蛋白(与阿尔茨海默氏病相关)的产生。
大鼠 Mouse Il18 分子靶点信息
- 分子名:Il18, interleukin 18
- 别称:
- IFN-gamma-inducing factor
- IL-1 gamma
- IL-18
- interferon gamma-inducing factor
- interferon-gamma-inducing factor
- interleukin-1 gamma
- interleukin-18
- 基因序列:NCBI_Gene: 29197
- 蛋白序列:
大鼠 Rat Il18 靶点分子功能(预测)
Predicted to enable cytokine activity and interleukin-18 receptor binding activity. Involved in several processes, including cellular response to hormone stimulus; positive regulation of cell population proliferation; and positive regulation of cytokine production. Located in apical plasma membrane; cytoplasm; and extracellular space. Used to study brain edema; fatty liver disease; heart disease; status epilepticus; and vasculitis. Biomarker of several diseases, including cardiac arrest; ischemia (multiple); lung disease (multiple); perinatal necrotizing enterocolitis; and urinary tract infection. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; allergic rhinitis; autoimmune disease (multiple); biliary atresia; and hepatitis B. Orthologous to human IL18 (interleukin 18).
引用文献统计
该产品被引用的文献总数为:6
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影响因子:1.6刊物:NEUROREPORT发表日期:2024-07-09 - Multi-omics integrated analysis indicated that non-polysaccharides of Sijunzi decoction ameliorated spleen deficiency syndrome via regulating microbiota-gut-metabolites axis and exerted synergistic compatibility
影响因子:4.8刊物:JOURNAL OF ETHNOPHARMACOLOGY发表日期:2024-05-01 - Mechanistic study of Huangqi Guizhi Wuwu decoction amelioration of doxorubicin-induced cardiotoxicity by reducing oxidative stress and inhibiting cellular pyroptosis
影响因子:6.9刊物:BIOMEDICINE & PHARMACOTHERAPY发表日期:2024-04-30 - Acupuncture ameliorates depression-like behavior of poststroke depression model rats through the regulation of gut microbiota and NLRP3 inflammasome in the colon
影响因子:1.6刊物:NEUROREPORT发表日期:2023-09-06 - Acupuncture ameliorates depression-like behavior of poststroke depression model rats through the regulation of gut microbiota and NLRP3 inflammasome in the colon
影响因子:1.6刊物:NEUROREPORT发表日期:http://2023-09-06