Mouse IFN-γ Standard (小鼠γ干扰素 标准品)

IFNG 分子靶点信息概述

• 分子名：IFNG, interferon gamma
• 基因家族：Interferons

IFNG 分子靶点综述

IFN-γ主要由Th1型细胞产生，属于II型细胞因子中干扰素家族中的一员，是一类分泌型糖蛋白，由143个氨基酸组成，相对分子质量是16942。IFN-γ主要由活化的T细胞和NK细胞产生，具有调节机体免疫状态，介导细胞免疫，加强受体介导的吞噬功能，增强巨噬细胞和中性粒细胞的杀伤活性，具有抗病毒感染及抗肿瘤等生物学活性。

小鼠 Mouse Ifng 分子靶点信息

• 分子名：Ifng, interferon gamma
• 别称：
  • Ifg
  • IFN-gamma
• 基因序列：NCBI_Gene: 15978
• 蛋白序列：
  • UniprotKB: P01580
  • UniprotKB: A0A7R8C347
  • UniprotKB: A3RL32
  • UniprotKB: C4NUL9
  • UniprotKB: C4NUM1
  • UniprotKB: Q6TDH0

小鼠 Mouse Ifng 靶点分子功能（预测）

Enables cytokine activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of macromolecule metabolic process; and regulation of generation of precursor metabolites and energy. Acts upstream of or within several processes, including CD8-positive, alpha-beta T cell differentiation involved in immune response; defense response to other organism; and positive regulation of macromolecule metabolic process. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Used to study several diseases, including aplastic anemia; hepatitis; malaria; medulloblastoma; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including allergic rhinitis; ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; and leukemia (multiple). Orthologous to human IFNG (interferon gamma).