EK1101S

Human sCD14 Standard (人可溶性CD14 标准品)

¥280.00

分子靶点：CD14
种属：人 (Human)
试剂盒：EK1101
保存：短期4℃保存，长期-20℃保存
运输条件：4℃蓝冰运输

在售SKU:70-EK1101S, 人, 可溶性, CD14

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本产品只包含标准品试剂，如需购买试剂盒请点击下图
Human sCD14 ELISA Kit检测试剂盒（酶联免疫吸附法）
分子信息
CD14 分子靶点信息概述
CD14 分子靶点综述
- 人 Human CD14 分子靶点信息
- 人 Human CD14靶点分子功能（预测）

本产品只包含标准品试剂，如需购买试剂盒请点击下图

- EK1101 5 Citations
- ELISA试剂盒
- Human sCD14 ELISA Kit检测试剂盒（酶联免疫吸附法）
- ¥1,600.00 – ¥2,650.00

商品名	Human sCD14 Standard (人可溶性CD14 标准品)
组分	人sCD14 标准品
板式	管
保存	短期4℃，长期-20℃保存
运输条件	4℃蓝冰运输

分子信息

概述人 CD14 靶点信息

CD14 分子靶点信息概述

分子名：CD14, CD14 molecule
基因家族：CD molecules; Scavenger receptors
全称：CD14 antigen

CD14 分子靶点综述

CD14是表达于单核细胞、滤泡间巨噬细胞和树突细胞亚群表面的糖蛋白。CD14与MD-2(LY)和TLR4形成受体复合物，可特异性地对LPS产生应答、传导信号。CD14/MD-2/TLR4受体复合物通过MyD88、TIRAP和TRAF6传导信号，最后激活NF-κB。

人 Human CD14 分子靶点信息

分子名：CD14, CD14 molecule
别称：
- cd14 antigen
- monocyte differentiation antigen CD14
- myeloid cell-specific leucine-rich glycoprotein
基因序列：NCBI_Gene: 929
蛋白序列：UniProtKB: P08571

人 Human CD14靶点分子功能（预测）

Enables lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in cellular response to bacterial lipopeptide; positive regulation of NIK/NF-kappaB signaling; and positive regulation of interleukin-8 production. Acts upstream of or within cellular response to lipopolysaccharide; cellular response to lipoteichoic acid; and positive regulation of tumor necrosis factor production. Located in Golgi apparatus and membrane raft. Is anchored component of external side of plasma membrane. Part of lipopolysaccharide receptor complex. Implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and pulmonary tuberculosis. Biomarker of several diseases, including biliary atresia; cystic fibrosis; lung disease (multiple); perinatal necrotizing enterocolitis; and polycystic kidney disease (multiple).