Anti-Rat Foxp3, PE (Clone: FJK-16s) 检测试剂
¥1,380.00 – ¥2,880.00
- 分子靶点:FOXP3, IPEX
- 种属:大鼠 (Rat)
- 标记:PE
- 亚型:Rat IgG2a, κ
- 克隆号:FJK-16s
在售SKU, 70-F31FP302-25, 70-F31FP302-100, F31FP302
商品名 |
Anti-Rat Foxp3, PE (Clone: FJK-16s) 检测试剂 |
---|---|
靶点 | |
标记 |
PE |
仪器 |
适用488nm, 532nm, 561nm激光器的流式细胞仪 |
亚型 |
Rat IgG2a, κ |
克隆号 |
FJK-16s |
推荐应用 |
流式检测 |
用量 |
5 μL /Test |
纯化 |
亲和层析 |
储存液 |
含0.2% BSA和 0.2% ProClin950的磷酸盐缓冲液(pH7.2) |
保存条件 |
2 - 8℃避光,切勿冻存 |
结果示例

图 - 以大鼠血液CD4阳性细胞设门进行分析的结果示例(需要配合使用Transcription Factor Fixation/Permeabilization Buffer),左图为Anti-Rat CD4, APC和Rat IgG2a, PE染色结果,右图为Anti-Rat CD4, APC和Anti-Rat Foxp3, PE染色结果。
分子信息
FOXP3 分子靶点信息概述
- 分子名:FOXP3, forkhead box P3
- 基因家族:Forkhead boxes
- 别名:JM2; XPID; AIID; PIDX; DIETER; SCURFIN
- 曾用名:IPEX
- 全称:immune dysregulation, polyendocrinopathy, enteropathy, X-linked
FOXP3 分子靶点综述
FoxP3蛋白是转录因子叉头家族的成员之一,表达于调节性T细胞(Regulatory T Cells, Treg),其发育和功能受到叉头蛋白的影响。T细胞中FoxP3的异常表达会抑制其活性和细胞因子分泌。
大鼠 Rat Foxp3 分子靶点信息
- 分子名:Foxp3, forkhead box P3
- 别称:
- forkhead box protein P3
- LOC317382
- RGD1562112
- similar to scurfin
- 基因序列:NCBI_Gene: 317382
- 蛋白序列:
大鼠 Rat Foxp3 靶点分子功能(预测)
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; NFAT protein binding activity; and enzyme binding activity. Involved in several processes, including establishment of endothelial blood-brain barrier; negative regulation of defense response to virus; and response to rapamycin. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Used to study intrahepatic cholangiocarcinoma. Biomarker of Korean hemorrhagic fever; asthma; bronchiolitis obliterans; hypertension; and hypothyroidism. Human ortholog(s) of this gene implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Orthologous to human FOXP3 (forkhead box P3).