Anti-Human FoxP3, PE (Clone:PCH101)流式抗体 (新品)
¥1,192.00 – ¥2,640.00
- 分子靶点:FOXP3, IPEX
- 种属:人 (Human)
- 标记:PE
- 亚型:Rat IgG2a, κ
- 克隆号:PCH101
在售SKU, 70-AH0F04-20, 70-AH0F04-50, 70-AH0F04-100, AH0F04, 70-F11FP302-25, 70-F11FP302-100
| 商品名 | Anti-Human FoxP3, PE (Clone:PCH101)流式抗体 | 
|---|---|
| 靶点 | |
| 标记 | PE | 
| 仪器 | 适用488nm, 532nm, 561nm激光器的流式细胞仪 | 
| 亚型 | Rat IgG2a, κ | 
| 克隆号 | PCH101 | 
| 推荐应用 | 流式检测 | 
| 用量 | 5 μL /Test | 
| 纯化 | 亲和层析 | 
| 储存液 | 含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2) | 
| 保存条件 | 2 - 8℃避光,切勿冻存 | 
结果示例

图 - 人抗凝血染色 Anti-Human FoxP3, PE (F11FP302) 和 Anti-Human CD4, FITC (F11004B01) 的结果。已排除黏连细胞。
分子信息
FOXP3 分子靶点信息概述
- 分子名:FOXP3, forkhead box P3
- 基因家族:Forkhead boxes
- 别名:JM2; XPID; AIID; PIDX; DIETER; SCURFIN
- 曾用名:IPEX
- 全称:immune dysregulation, polyendocrinopathy, enteropathy, X-linked
FOXP3 分子靶点综述
FoxP3蛋白是转录因子叉头家族的成员之一,表达于调节性T细胞(Regulatory T Cells, Treg),其发育和功能受到叉头蛋白的影响。T细胞中FoxP3的异常表达会抑制其活性和细胞因子分泌。
人 Human FOXP3 分子靶点信息
- 分子名:FOXP3, forkhead box P3
- 别称:
- AIID
- DIETER
- forkhead box protein P3
- FOXP3delta7
- immune dysregulation, polyendocrinopathy, enteropathy, X-linked
- immunodeficiency, polyendocrinopathy, enteropathy, X-linked
- IPEX
- JM2
- MGC141961
- MGC141963
- PIDX
- scurfin
- XPID
 
- 基因序列:NCBI_Gene: 50943
- 蛋白序列:UniProtKB: Q9BZS1
人 Human FOXP3靶点分子功能(预测)
Enables several functions, including NFAT protein binding activity; enzyme binding activity; and protein homodimerization activity. Involved in several processes, including negative regulation of T cell activation; regulation of gene expression; and regulation of histone modification. Located in cytoplasm and nucleoplasm. Implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Biomarker of several diseases, including adult T-cell leukemia; anogenital venereal wart; chlamydia; liver disease (multiple); and tuberculosis (multiple).
 
								

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