F11FP302

Anti-Human FoxP3, PE (Clone:PCH101)流式抗体 (新品)

¥1,192.00¥2,640.00

  • 分子靶点:FOXP3, IPEX
  • 种属:人 (Human)
  • 标记:PE
  • 亚型:Rat IgG2a, κ
  • 克隆号:PCH101

在售SKU, 70-AH0F04-20, 70-AH0F04-50, 70-AH0F04-100, AH0F04, 70-F11FP302-25, 70-F11FP302-100


商品名

Anti-Human FoxP3, PE (Clone:PCH101)流式抗体

靶点

FOXP3, IPEX

标记

PE

仪器

适用488nm, 532nm, 561nm激光器的流式细胞仪

亚型

Rat IgG2a, κ

克隆号

PCH101

推荐应用

流式检测

用量

5 μL /Test

纯化

亲和层析

储存液

含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)

保存条件

2 - 8℃避光,切勿冻存

结果示例

Anti-Human FoxP3, PE (Clone:PCH101)流式抗体 - 结果示例图片
结果示例

图 - 人抗凝血染色 Anti-Human FoxP3, PE (F11FP302) 和 Anti-Human CD4, FITC (F11004B01) 的结果。已排除黏连细胞。

分子信息

概述人 FOXP3, IPEX 靶点信息

FOXP3 分子靶点信息概述

  • 分子名:FOXP3, forkhead box P3
  • 基因家族:Forkhead boxes
  • 别名:JM2; XPID; AIID; PIDX; DIETER; SCURFIN
  • 曾用名:IPEX
  • 全称:immune dysregulation, polyendocrinopathy, enteropathy, X-linked

FOXP3 分子靶点综述

FoxP3蛋白是转录因子叉头家族的成员之一,表达于调节性T细胞(Regulatory T Cells, Treg),其发育和功能受到叉头蛋白的影响。T细胞中FoxP3的异常表达会抑制其活性和细胞因子分泌。

人 Human FOXP3 分子靶点信息

  • 分子名:FOXP3, forkhead box P3
  • 别称:
    • AIID
    • DIETER
    • forkhead box protein P3
    • FOXP3delta7
    • immune dysregulation, polyendocrinopathy, enteropathy, X-linked
    • immunodeficiency, polyendocrinopathy, enteropathy, X-linked
    • IPEX
    • JM2
    • MGC141961
    • MGC141963
    • PIDX
    • scurfin
    • XPID
  • 基因序列:NCBI_Gene: 50943
  • 蛋白序列:UniProtKB: Q9BZS1

人 Human FOXP3靶点分子功能(预测)

Enables several functions, including NFAT protein binding activity; enzyme binding activity; and protein homodimerization activity. Involved in several processes, including negative regulation of T cell activation; regulation of gene expression; and regulation of histone modification. Located in cytoplasm and nucleoplasm. Implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Biomarker of several diseases, including adult T-cell leukemia; anogenital venereal wart; chlamydia; liver disease (multiple); and tuberculosis (multiple).

引用文献统计

流式抗体操作视频资源

查看更多流式抗体操作视频资源

流式抗体相关实验方案

查看更多流式抗体相关实验方案

流式抗体操作常见问题

查看更多流式抗体操作步骤技术文章