Anti-Human CD71, FITC(Clone:OKT9) (新品)
¥872.00 – ¥1,936.00
- 分子靶点:TFRC, CD71, TFR1
- 种属:人 (Human)
- 标记:FITC
- 亚型:Mouse IgG1, κ
- 克隆号:OKT9
在售SKU, 70-AH07101-20, 70-AH07101-50, 70-AH07101-100, AH07101, 70-F1107101-25, 70-F1107101-100
商品名 |
Anti-Human CD71, FITC(Clone:OKT9) |
---|---|
靶点 | |
标记 |
FITC |
仪器 |
适用488nm激光器的流式细胞仪 |
亚型 |
Mouse IgG1, κ |
克隆号 |
OKT9 |
推荐应用 |
流式检测 |
用量 |
5 μL /Test |
纯化 |
亲和层析 |
储存液 |
含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2) |
保存条件 |
2 - 8℃避光,切勿冻存 |
结果示例


图 - 正常人外周血经淋巴细胞分离液(LSM01) 分离,以 Anti-Human CD3, Functional Grade (F1100300) 和 Anti-Human CD28, Functional Grade (F1102800) 刺激培养 48 小时后,染色 Anti-Human CD25, APC (Clone:BC96) (F1102503) 和 Anti-Human CD71, FITC (F1107101)的结果。以 FSC/SSC 中的增殖的淋巴细胞设门进行分析。
分子信息
TFRC 分子靶点信息概述
- 分子名:TFRC, transferrin receptor
- 基因家族:CD molecules; M28 metallopeptidases
- 别名:CD71; TFR1; p90
- 全称:transferrin receptor (p90, CD71)
TFRC 分子靶点综述
转铁蛋白受体 CD71 是一种 1180 kDa 的 II 型跨膜蛋白,在细胞表面以同源二聚体的形式存在,对细胞生长至关重要。CD71 表达于未成熟的增殖中的细胞,在静息的成熟淋巴细胞中表达水平较低。抗原或丝裂原刺激的 T 细胞和 B 细胞可上调 CD71 的表达。
人 Human TFRC 分子靶点信息
- 分子名:TFRC, transferrin receptor
- 别称:
- CD71
- IMD46
- p90
- T9
- TFR
- TFR1
- TR
- transferrin receptor (p90, CD71)
- transferrin receptor protein 1
- TRFR
- 基因序列:NCBI_Gene: 7037
- 蛋白序列:UniProtKB: P02786
人 Human TFRC靶点分子功能(预测)
Enables several functions, including double-stranded RNA binding activity; protein homodimerization activity; and transferrin receptor activity. Involved in several processes, including negative regulation of mitochondrial fusion; positive regulation of NF-kappaB transcription factor activity; and positive regulation of lymphocyte activation. Acts upstream of or within cellular response to xenobiotic stimulus. Located in several cellular components, including basolateral plasma membrane; clathrin-coated pit; and endosome. Is integral component of plasma membrane. Part of HFE-transferrin receptor complex. Implicated in breast carcinoma; immunodeficiency 46; multiple myeloma; and ovarian cancer. Biomarker of breast cancer; carcinoma (multiple); iron deficiency anemia; and prostate cancer.