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EK317HSS

Rat IL-17A High Sensitivity Standard (大鼠白细胞介素17A高敏 标准品)

¥280.00

  • 分子靶点：IL17A, IL17, CTLA8
  • 种属：大鼠 (Rat)
  • 试剂盒：EK317HS
  • 保存：短期4℃保存，长期-20℃保存
  • 运输条件：4℃蓝冰运输

在售SKU:70-EK317HSS


 Vial

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商品名

Rat IL-17A High Sensitivity Standard (大鼠白细胞介素17A高敏 标准品)
组分

大鼠IL-17AA 标准品
板式

管
保存

短期4℃，长期-20℃保存
运输条件

4℃蓝冰运输

分子信息

概述大鼠 IL17A, IL17, CTLA8 靶点信息

IL17A 分子靶点信息概述

  • 分子名：IL17A, interleukin 17A
  • 基因家族：Interleukins
  • 别名：IL-17A; IL-17
  • 曾用名：CTLA8; IL17
  • 全称：cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

IL17A 分子靶点综述

IL-17主要由Th17型细胞产生，是目前已发现的30余种白细胞介素中的一员，按序号排在第17位。该家族包括6个成员配体(IL-17A ~ IL-17F)和5个受体(IL-17RA ~ IL-17RD和SEF)。IL-17是一种主要由活化的T细胞产生的致炎细胞因子，可以促进T细胞的激活和刺激上皮细胞、内皮细胞、成纤维细胞产生多种细胞因子，从而导致炎症的产生。

大鼠 Rat Il17a 分子靶点信息

  • 分子名：Il17a, interleukin 17A
  • 别称：
    • CTLA-8
    • cytotoxic T-lymphocyte-associated antigen 8
    • hypothetical protein LOC301289
    • IL-17
    • IL-17A
    • Il17
    • interleukin 17
    • Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
    • interleukin-17A
    • LOC301289
    • similar to Interleukin-17 precursor (IL-17) (Cytotoxic T lymphocyte-associated antigen 8) (CTLA-8)
  • 基因序列：NCBI_Gene: 301289
  • 蛋白序列：

大鼠 Rat Il17a 靶点分子功能（预测）

Predicted to enable protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including cellular response to glucocorticoid stimulus; positive regulation of necrotic cell death; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and extracellular space. Used to study anti-basement membrane glomerulonephritis; congestive heart failure; myocarditis; pleurisy; and uveitis. Biomarker of several diseases, including acute necrotizing pancreatitis; inflammatory bowel disease (multiple); lipoid nephrosis; lung disease (multiple); and periodontal disease (multiple). Human ortholog(s) of this gene implicated in Mycobacterium avium complex disease; autoimmune disease (multiple); bronchial disease (multiple); macular degeneration; and rhinitis (multiple). Orthologous to human IL17A (interleukin 17A).

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