Human Vitamin D BP Standard (人维生素D结合蛋白 标准品)

GC 分子靶点信息概述

• 分子名：GC, GC vitamin D binding protein
• 别名：DBP; VDBP; hDBP
• 全称：group-specific component (vitamin D binding protein); GC, vitamin D binding protein

GC 分子靶点综述

维生素D结合蛋白(VitaminDBP)也称为gc(组特异性成份)球蛋白，与人血清白蛋白和甲胎蛋白均属于白蛋白基因家族。它具有多种功能，存在于血浆、腹水、脑脊髓液和很多类型细胞的表面。它与维生素D及其代谢产物结合，将它们转运至靶组织。作为Gc蛋白衍生的巨噬细胞活化因子，VitaminDBP可用于癌症治疗，活化巨噬细胞抵抗肿瘤细胞。

人 Human GC 分子靶点信息

• 分子名：GC, GC vitamin D binding protein
• 别称：
  • DBP
  • DBP-maf
  • DBP/GC
  • epididymis secretory protein Li 51
  • gc protein-derived macrophage activating factor
  • gc-globulin
  • Gc-MAF
  • GcMAF
  • GRD3
  • group-specific component (vitamin D binding protein)
  • HEL-S-51
  • VDB
  • VDBG
  • VDBP
  • vitamin D-binding alpha-globulin
  • vitamin D-binding protein
  • vitamin D-binding protein-macrophage activating factor
• 基因序列：NCBI_Gene: 2638
• 蛋白序列：UniProtKB: P02774

人 Human GC靶点分子功能（预测）

Enables actin binding activity and calcidiol binding activity. Predicted to be involved in vitamin transport. Predicted to act upstream of or within vitamin D metabolic process. Located in blood microparticle and extracellular exosome. Implicated in several diseases, including autoimmune disease (multiple); chronic obstructive pulmonary disease; hepatocellular carcinoma; human immunodeficiency virus infectious disease; and rheumatic fever. Biomarker of several diseases, including autoimmune disease (multiple); dengue disease; diabetic retinopathy; hepatic encephalopathy; and sciatic neuropathy.