Human EGF Standard (人表皮生长因子体 标准品)
¥180.00
- 分子靶点:EGF, epidermal growth factor
- 种属:人 (Human)
- 试剂盒:EK193
- 保存:短期4℃保存,长期-20℃保存
- 运输条件:4℃蓝冰运输
在售SKU:70-EK193S
文章目录[隐藏]
本产品只包含标准品试剂,如需购买试剂盒请点击下图
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- EK193 12 Citations
- ELISA试剂盒
Human EGF ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥2,650.00
商品名 |
Human EGF Standard (人表皮生长因子体 标准品) |
---|---|
组分 |
人EGF标准品 |
板式 |
管 |
保存 |
短期4℃,长期-20℃保存 |
运输条件 |
4℃蓝冰运输 |
分子信息
EGF 分子靶点信息概述
- 分子名:EGF, epidermal growth factor
- 全称:Pro-epidermal growth factor; epidermal growth factor (beta-urogastrone)
EGF 分子靶点综述
表皮生长因子(EGF)是一种通过与其受体EGFR结合,刺激细胞生长、增殖和分化的生长因子。EGF是小分子量多肽,最迟从小鼠下颌下腺纯化得到,随后在很多人的组织中均有发现,包括下颌下腺和腮腺。由饮食中的无机碘调控的唾液EGF在维持奥罗食管和胃组织健全方面具有重要的生理作用。唾液EGF的生理作用包括治愈口腔和胃溃疡、抑制胃酸分泌、刺激DNA合成以及保护粘膜免受腔内有害因素(如胃酸、胆汁酸、胃蛋白酶和胰蛋白酶)和物理、化学和细菌因素破坏。在某些通常与受体的突变和功能异常(如不依赖于EGF水平或与EGF结合的组成性受体信号传导)有关的癌症中,可观察到EGF受体活性增强。
人 Human EGF 分子靶点信息
- 分子名:EGF, epidermal growth factor
- 别称:
- beta-urogastrone
- HOMG4
- pro-epidermal growth factor
- URG
- 基因序列:NCBI_Gene: 1950
- 蛋白序列:UniProtKB: P01133
人 Human EGF靶点分子功能(预测)
Enables growth factor activity and guanyl-nucleotide exchange factor activity. Involved in several processes, including ERK1 and ERK2 cascade; positive regulation of macromolecule metabolic process; and positive regulation of signal transduction. Acts upstream of or within positive regulation of cell population proliferation. Located in extracellular exosome. Implicated in several diseases, including Zollinger-Ellison syndrome; hepatobiliary system cancer (multiple); high grade glioma (multiple); lung non-small cell carcinoma (multiple); and primary hypomagnesemia (multiple). Biomarker of several diseases, including acute kidney failure; lupus nephritis; neurodegenerative disease (multiple); pancreatic cancer (multiple); and pancreatitis.