Human Pro-Collagen I α1 Standard (人I型前胶原蛋白标准品)

人 Human COL1A1 分子靶点信息

• 分子名：COL1A1, collagen type I alpha 1 chain
• 别称：
  • alpha-1 type I collagen
  • alpha1(I) procollagen
  • CAFYD
  • collagen alpha 1 chain type I
  • collagen alpha-1(I) chain
  • collagen alpha-1(I) chain preproprotein
  • collagen of skin, tendon and bone, alpha-1 chain
  • collagen type I alpha 1
  • collagen, type I, alpha 1
  • EDSARTH1
  • EDSC
  • OI1
  • OI2
  • OI3
  • OI4
  • pro-alpha-1 collagen type 1
  • type I proalpha 1
  • type I procollagen alpha 1 chain
• 基因序列：NCBI_Gene: 1277
• 蛋白序列：UniProtKB: P02452

人 Human COL1A1靶点分子功能（预测）

Enables identical protein binding activity; platelet-derived growth factor binding activity; and protease binding activity. Involved in several processes, including collagen biosynthetic process; collagen fibril organization; and skin morphogenesis. Acts upstream of or within skeletal system development. Located in extracellular space. Part of collagen type I trimer. Colocalizes with collagen-containing extracellular matrix. Implicated in several diseases, including Ehlers-Danlos syndrome arthrochalasia type 1; aggressive periodontitis; bone disease (multiple); cutaneous leishmaniasis; and dentinogenesis imperfecta. Biomarker of several diseases, including alcoholic hepatitis; autoimmune disease (multiple); chronic obstructive pulmonary disease; end stage renal disease; and lupus nephritis.