EK301BEGB

EasyGo!™ Rat IL-1β One-Step ELISA Kit 检测试剂盒(酶联免疫吸附法)

¥3,650.00

在售SKU: 70-EK301BEGB-48, 70-EK301BEGB-96, EK301BEGB, 一步法, 一步法ELISA, 一步法试剂盒, 一步法ELISA试剂盒

  • 分子靶点:IL1B
  • 种属:大鼠
  • 样本类型:细胞上清样本
  • 检测样本体积:100μL
  • 灵敏度:4.8pg/mL
  • 检测范围:31.25-2000pg/mL
  • 回收率:无数据

96T

EK301BEGB-96

-+

ELISA试剂盒详细信息

商品名EasyGo!™ Rat IL-1β One-Step ELISA Kit 检测试剂盒(酶联免疫吸附法)
种属大鼠
靶点IL1B
检测方法双抗体夹心法
检测样本类型细胞上清样本
检测样本体积100μL
灵敏度4.8pg/mL
线性范围31.25-2000pg/mL
精密度板内变异系数:3.4%-4.4%;板间变异系数:2.8%-5.7%
回收率无数据
板式
保存条件2-8℃保存。已拆开:标准品-20℃保存,其它4℃。
运输条件2-8℃冰袋运输
检测原理

分子信息

概述大鼠 IL1B, IL1-β, IL1F2 靶点信息

IL1B 分子靶点信息概述

  • 分子名:IL1B, interleukin 1 beta
  • 基因家族:Interleukins
  • 别名:IL1F2; IL-1B; IL1-BETA

IL1B 分子靶点综述

白细胞介素1(IL-1)是17kDa的胞外多肽,分为IL-1α和IL-1β两种蛋白。IL-1β是活化的巨噬细胞分泌的蛋白前体,通过caspase1(CASP1/ICE)水解产生的活化形式。该细胞因子是炎症反应的重要介导者,参与许多细胞活性,包括细胞增殖、分化和凋亡。IL-1是一类重要的蛋白家族,它们由生物活化的单核细胞所衍生,参与炎症反应和免疫应答。IL-1β表达升高会产生各种不同的自身炎症综合征,最显著的是单基因条件称为CAPS,是由于触发IL-1β加工的炎性体受体NLRP3发生突变而引起的。本试剂盒用来检测人IL-1β的成熟形式和未裂解的前体形式。

大鼠 Rat Il1b 分子靶点信息

大鼠 Rat Il1b 靶点分子功能(预测)

Enables cytokine activity. Involved in several processes, including positive regulation of intracellular signal transduction; regulation of gene expression; and regulation of neurogenesis. Located in extracellular space. Used to study several diseases, including artery disease (multiple); brain disease (multiple); glomerulonephritis (multiple); interstitial lung disease (multiple); and kidney failure (multiple). Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); brain disease (multiple); kidney failure (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Orthologous to human IL1B (interleukin 1 beta).