Anti-Mouse CD127 (IL-7Rα), PE (Clone:A7R34) 流式抗体 (新品)
¥792.00 – ¥1,760.00
- 分子靶点:CD127, IL7R, IL7RA
- 种属:小鼠 (Mouse)
- 标记:PE
- 亚型:Rat IgG2a, κ
- 克隆号:A7R34
在售SKU, 70-AM012704-20, 70-AM012704-50, 70-AM012704-100, AM012704, 70-F2112702-25, 70-F2112702-100
商品名 |
Anti-Mouse CD127 (IL-7Rα), PE (Clone:A7R34) 流式抗体 |
---|---|
靶点 | |
标记 |
PE |
仪器 |
适用488nm, 532nm, 561nm激光器的流式细胞仪 |
亚型 |
Rat IgG2a, κ |
克隆号 |
A7R34 |
推荐应用 |
流式检测 |
用量 |
5 μL /Test |
纯化 |
亲和层析 |
储存液 |
含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2) |
保存条件 |
2 - 8℃避光,切勿冻存 |
分子信息
IL7R 分子靶点信息概述
- 分子名:IL7R, interleukin 7 receptor
- 基因家族:CD molecules; Fibronectin type III domain containing; Interleukin receptors
- 别名:CD127; IL7RA
IL7R 分子靶点综述
CD127是白细胞介素7受体α链,与CD132 (β链)共同形成高亲和力的受体。CD127表达于大部分T细胞,但在T细胞活化后可发生降低,也表达在B细胞前体和单核细胞。CD127的表达对T淋巴细胞的成熟、维持及免疫应答发挥着重要作用。
小鼠 Mouse Il7r 分子靶点信息
- 分子名:Il7r, interleukin 7 receptor
- 别称:
- CD127
- IL-7 receptor alpha chain
- IL-7Ralpha
- 基因序列:NCBI_Gene: 16197
- 蛋白序列:
小鼠 Mouse Il7r 靶点分子功能(预测)
Predicted to enable cytokine receptor activity. Involved in defense response to Gram-positive bacterium. Acts upstream of or within several processes, including hematopoietic or lymphoid organ development; negative regulation of T cell mediated cytotoxicity; and positive regulation of T cell differentiation in thymus. Located in external side of plasma membrane. Is expressed in adrenal gland; brain; early conceptus; hemolymphoid system; and lymphatic system. Human ortholog(s) of this gene implicated in severe combined immunodeficiency and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human IL7R (interleukin 7 receptor).