F2112702

Anti-Mouse CD127 (IL-7Rα), PE (Clone:A7R34) 流式抗体 (新品)

¥792.00¥1,760.00

  • 分子靶点:CD127, IL7R, IL7RA
  • 种属:小鼠 (Mouse)
  • 标记:PE
  • 亚型:Rat IgG2a, κ
  • 克隆号:A7R34

在售SKU, 70-AM012704-20, 70-AM012704-50, 70-AM012704-100, AM012704, 70-F2112702-25, 70-F2112702-100


商品名

Anti-Mouse CD127 (IL-7Rα), PE (Clone:A7R34) 流式抗体

靶点

CD127, IL7R, IL7RA

标记

PE

仪器

适用488nm, 532nm, 561nm激光器的流式细胞仪

亚型

Rat IgG2a, κ

克隆号

A7R34

推荐应用

流式检测

用量

5 μL /Test

纯化

亲和层析

储存液

含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)

保存条件

2 - 8℃避光,切勿冻存

分子信息

概述小鼠 CD127, IL7R, IL7RA 靶点信息

IL7R 分子靶点信息概述

  • 分子名:IL7R, interleukin 7 receptor
  • 基因家族:CD molecules; Fibronectin type III domain containing; Interleukin receptors
  • 别名:CD127; IL7RA

IL7R 分子靶点综述

CD127是白细胞介素7受体α链,与CD132 (β链)共同形成高亲和力的受体。CD127表达于大部分T细胞,但在T细胞活化后可发生降低,也表达在B细胞前体和单核细胞。CD127的表达对T淋巴细胞的成熟、维持及免疫应答发挥着重要作用。

小鼠 Mouse Il7r 分子靶点信息

小鼠 Mouse Il7r 靶点分子功能(预测)

Predicted to enable cytokine receptor activity. Involved in defense response to Gram-positive bacterium. Acts upstream of or within several processes, including hematopoietic or lymphoid organ development; negative regulation of T cell mediated cytotoxicity; and positive regulation of T cell differentiation in thymus. Located in external side of plasma membrane. Is expressed in adrenal gland; brain; early conceptus; hemolymphoid system; and lymphatic system. Human ortholog(s) of this gene implicated in severe combined immunodeficiency and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human IL7R (interleukin 7 receptor).

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