Human PIGF Standard (人胎盘生长因子 标准品)

PGF 分子靶点信息概述

• 分子名：PGF, placental growth factor
• 基因家族：VEGF family
• 别名：PlGF-2; SHGC-10760; D12S1900; PIGF; PLGF; PlGF
• 曾用名：PGFL
• 全称：placental growth factor-like; placental growth factor, vascular endothelial growth factor-related protein; placenta growth factor

PGF 分子靶点综述

胎盘生长因子(PGF)是血管内皮生长因子(VEGF)亚家族中的一员，是血管生成、特别是胚胎发育过程中的关键分子。妊娠期间，胎盘滋养层是 PIGF 的主要来源。许多其它组织，包括绒毛滋养细胞也能表达 PIGF。人类动脉粥样硬化损伤中的 PIGF 表达与斑块炎症和新生血管生长有关。在早发型和晚发型子痫前期，母体血清中的 sFlt-1 水平较高、PGF 水平较低。

人 Human PGF 分子靶点信息

• 分子名：PGF, placental growth factor
• 别称：
  • D12S1900
  • PGFL
  • PIGF
  • placenta growth factor
  • placental growth factor-like
  • placental growth factor, vascular endothelial growth factor-related protein
  • PLGF
  • PlGF-2
  • SHGC-10760
• 基因序列：NCBI_Gene: 5228
• 蛋白序列：UniProtKB: P49763

人 Human PGF靶点分子功能（预测）

Enables growth factor activity. Involved in positive regulation of cell population proliferation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Implicated in several diseases, including brain ischemia; diabetic neuropathy; glioblastoma; myocardial infarction; and pancreatic endocrine carcinoma. Biomarker of several diseases, including artery disease (multiple); autoimmune disease of musculoskeletal system (multiple); epilepsy (multiple); limited scleroderma; and pancreatic endocrine carcinoma.