F1101402

Anti-Human CD14, PE (Clone:61D3)检测试剂

¥1,000.00 – ¥2,200.00

说明书

分子靶点：CD14
种属：人 (Human)
标记：PE
亚型：Mouse IgG1, κ
克隆号：61D3

在售SKU, 70-AH01404-20, 70-AH01404-50, 70-AH01404-100, AH01404, 70-F1101402-25, 70-F1101402-100

文章目录[隐藏]

结果示例
分子信息
CD14 分子靶点信息概述
CD14 分子靶点综述
- 人 Human CD14 分子靶点信息
- 人 Human CD14靶点分子功能（预测）

商品名	Anti-Human CD14, PE (Clone:61D3)检测试剂
靶点	CD14
标记	PE
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Mouse IgG1, κ
克隆号	61D3
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血染色 Anti-Human CD14, PE (F1101402) 和 Anti-Human/Mouse CD11b, FITC(F11011B01)的结果。以 FSC/SSC 中的单核细胞设门进行分析。

分子信息

概述人 CD14 靶点信息

CD14 分子靶点信息概述

分子名：CD14, CD14 molecule
基因家族：CD molecules; Scavenger receptors
全称：CD14 antigen

CD14 分子靶点综述

CD14是表达于单核细胞、滤泡间巨噬细胞和树突细胞亚群表面的糖蛋白。CD14与MD-2(LY)和TLR4形成受体复合物，可特异性地对LPS产生应答、传导信号。CD14/MD-2/TLR4受体复合物通过MyD88、TIRAP和TRAF6传导信号，最后激活NF-κB。

人 Human CD14 分子靶点信息

分子名：CD14, CD14 molecule
别称：
- cd14 antigen
- monocyte differentiation antigen CD14
- myeloid cell-specific leucine-rich glycoprotein
基因序列：NCBI_Gene: 929
蛋白序列：UniProtKB: P08571

人 Human CD14靶点分子功能（预测）

Enables lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in cellular response to bacterial lipopeptide; positive regulation of NIK/NF-kappaB signaling; and positive regulation of interleukin-8 production. Acts upstream of or within cellular response to lipopolysaccharide; cellular response to lipoteichoic acid; and positive regulation of tumor necrosis factor production. Located in Golgi apparatus and membrane raft. Is anchored component of external side of plasma membrane. Part of lipopolysaccharide receptor complex. Implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and pulmonary tuberculosis. Biomarker of several diseases, including biliary atresia; cystic fibrosis; lung disease (multiple); perinatal necrotizing enterocolitis; and polycystic kidney disease (multiple).