DNA损伤修复研究系列产品

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https://www.liankebio.com/article-information_Newsletter-853.html

作者:Novus官网 发布日期:2015-02-08 10:00

DNA损伤修复在多种酶的作用下,生物细胞内的DNA分子受到损伤以后恢复结构的现象。DNA损伤修复的研究有助于了解基因突变的机制,衰老和癌变的原因,还可应用于环境致癌因子的检测。DNA修复可以引起抑癌基因的失活,原癌基因的激活,从而导致癌症的发生。人有超过130个基因与DNA的修复机制相关。
Novus提供大量与DNA损伤修复研究相关的产品,方便广大科研用户。

Customer Reviews
BP1 Antibody (NB100-304)

Application: IHC

Sample Tested: Mouse thymocytes

Species: Mouse

Results: I needed to localize DSB repair at a single locus, so IHC was combined with DNA FISH. Many other antibodies failed because DNA FISH requires heating the cells to 80 degrees C which denatures most proteins. This anti-53BP1 antibody resulted in discrete, bright foci regardless of FISH hybridization.

FANCD2 Antibody (NB100-182)

Application: Western blot Sample Tested: PD20 cell line Species: Human

Ogg1 Antibody (NB100-106)

Application: IHC

Sample Tested: Human foreskin, adult ski, engineered human skin, keratinocytes, HaCaT cells

Species: Human