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F21049B01

Anti-Mouse CD49b，FITC (Clone: HMa2) 流式抗体 (新品)

¥520.00 – ¥1,144.00

  • 分子靶点：CD49B, ITGA2
  • 种属：小鼠 (Mouse)
  • 标记：FITC
  • 亚型：Armenian Hamster IgG
  • 克隆号：HMa2

在售SKU, 70-AM049B01-20, 70-AM049B01-50, 70-AM049B01-100, AM049B01, 70-F21049B01-25, 70-F21049B01-100


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商品名

Anti-Mouse CD49b，FITC (Clone: HMa2) 流式抗体
靶点

CD49B, ITGA2
标记

FITC
仪器

适用488nm激光器的流式细胞仪
亚型

Armenian Hamster IgG
克隆号

HMa2
推荐应用

流式检测
用量

5 μL /Test
纯化

亲和层析
储存液

含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件

2 - 8℃避光，切勿冻存

结果示例

Anti-Mouse CD49b，FITC (Clone: HMa2) 流式抗体 - 结果示例图片
结果示例

图 - 图. ICR 小 鼠 脾 细 胞 染 色 Anti-Mouse NK1.1 (CD161), PE-Cy7 (AM16110) 和Anti-Mouse CD49b, FITC (AM049B01)的结果。已排除粘连细胞。

分子信息

概述小鼠 CD49B, ITGA2 靶点信息

ITGA2 分子靶点信息概述

  • 分子名：ITGA2, integrin subunit alpha 2
  • 基因家族：CD molecules; Integrin alpha subunits
  • 别名：CD49b
  • 曾用名：CD49B
  • 全称：alpha 2 subunit of VLA-2 receptor; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)

ITGA2 分子靶点综述

CD49b，也称为整合素α2，是一种150 kD膜表面糖蛋白。CD49b (整合素α2)与CD29 (整合素β1)非共价结合形成异质二聚体VLA-2即血小板糖蛋白Ia/IIa (CD49b/CD29)，可介导成熟巨核细胞和血小板与胶原之间的粘附。CD49b表达于血小板、肠上皮细胞、NK细胞、上皮细胞和活化T细胞等，在介导胞外基质细胞粘附中起着重要作用。

小鼠 Mouse Itga2 分子靶点信息

小鼠 Mouse Itga2 靶点分子功能（预测）

Enables amyloid-beta binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell migration; and positive regulation of cellular component organization. Predicted to act upstream of or within cell adhesion. Located in basal part of cell and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; eye; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; artery disease (multiple); blood platelet disease (multiple); diabetes mellitus (multiple); and von Willebrand's disease (multiple). Orthologous to human ITGA2 (integrin subunit alpha 2).

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