F2100407

Anti-Mouse CD4, mFluor 450 Clone: GK1.5流式抗体 (新品)

¥1,312.00¥2,664.00

  • 分子靶点:CD4
  • 种属:小鼠 (Mouse)
  • 标记:mFlour 450
  • 亚型:Rat IgG2b, κ
  • 克隆号:GK1.5

在售SKU, F2100407, 70-F2100407-25, 70-F2100407-100


100T

-+
商品名

Anti-Mouse CD4, mFluor 450 (Clone:GK1.5)流式抗体检测试剂

靶点

CD4

标记

mFlour 450

仪器

适用405nm激光器的流式细胞仪

亚型

Rat IgG2b, κ

克隆号

GK1.5

推荐应用

流式检测

用量

5 μL /Test

纯化

亲和层析

储存液

含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)

保存条件

2 - 8℃避光,切勿冻存

结果示例

Anti-Mouse CD4, mFluor 450 (Clone:GK1.5)流式抗体 - 结果示例图片
结果示例

图 - 小鼠脾脏细胞Anti-Mouse CD4, mFluor 450(Clone: GK1.5) (F2100407) 以全部细胞进行分析。

分子信息

概述小鼠 CD4 靶点信息

CD4 分子靶点信息概述

  • 分子名:CD4, CD4 molecule
  • 基因家族:CD molecules; V-set domain containing; C2-set domain containing
  • 全称:CD4 antigen (p55); T-cell surface glycoprotein CD4

CD4 分子靶点综述

CD4也称为T4,为55 kD的单链I型跨膜糖蛋白,表达于大部分胸腺细胞、T细胞亚群和单核/巨噬细胞。CD4作为免疫球蛋白超家族的一员,可识别与MHC II类分子结合的抗原,参与细胞-细胞互作、胸腺分化和信号传导。CD4是HIV的主要受体,可与HIV gp120结合。CD4与IL-16也有相互作用。

小鼠 Mouse Cd4 分子靶点信息

小鼠 Mouse Cd4 靶点分子功能(预测)

Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).