Anti-Mouse CD4, mFluor 450 Clone: GK1.5流式抗体 (新品)

CD4 分子靶点信息概述

• 分子名：CD4, CD4 molecule
• 基因家族：CD molecules; V-set domain containing; C2-set domain containing
• 全称：CD4 antigen (p55); T-cell surface glycoprotein CD4

CD4 分子靶点综述

CD4也称为T4，为55 kD的单链I型跨膜糖蛋白，表达于大部分胸腺细胞、T细胞亚群和单核/巨噬细胞。CD4作为免疫球蛋白超家族的一员，可识别与MHC II类分子结合的抗原，参与细胞-细胞互作、胸腺分化和信号传导。CD4是HIV的主要受体，可与HIV gp120结合。CD4与IL-16也有相互作用。

小鼠 Mouse Cd4 分子靶点信息

• 分子名：Cd4, CD4 antigen
• 别称：
  • L3T4
  • Ly-4
  • lymphocyte antigen 4
• 基因序列：NCBI_Gene: 12504
• 蛋白序列：
  • UniprotKB: P06332
  • UniprotKB: O55054
  • UniprotKB: P70443
  • UniprotKB: Q3TSV7

小鼠 Mouse Cd4 靶点分子功能（预测）

Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).