Anti-Human CD59, FITC (Clone:FOV9A2) (新品)
¥792.00 – ¥1,760.00
- 分子靶点:CD59
- 种属:人 (Human)
- 标记:FITC
- 亚型:Mouse IgG1, κ
- 克隆号:FOV9A2
在售SKU, 70-AH05901-20, 70-AH05901-50, 70-AH05901-100, AH05901, 70-F1105901-25, 70-F1105901-100
商品名 |
Anti-Human CD59, FITC (Clone:FOV9A2) |
---|---|
靶点 | |
标记 |
FITC |
仪器 |
适用488nm激光器的流式细胞仪 |
亚型 |
Mouse IgG1, κ |
克隆号 |
FOV9A2 |
推荐应用 |
流式检测 |
用量 |
5 μL /Test |
纯化 |
亲和层析 |
储存液 |
含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2) |
保存条件 |
2 - 8℃避光,切勿冻存 |
结果示例

图 - 人外周血染色 Anti-Human CD59, FITC(F1105901)(实线) 和 Mouse IgG1 κ Isotype Control, FITC(CMG101)(虚线)的结果。以 FSC/SSC 中的淋巴细胞设门进行分析。
分子信息
CD59 分子靶点信息概述
- 分子名:CD59, CD59 molecule (CD59 blood group)
- 基因家族:Blood group antigens; CD molecules; LY6/PLAUR domain containing; Complement system regulators and receptors
- 别名:16.3A5; EJ16; EJ30; EL32; G344; p18-20
- 曾用名:MIC11; MIN1; MSK21; MIN2; MIN3
- 全称:CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); CD59 antigen, complement regulatory protein; CD59 molecule, complement regulatory protein; CD59 molecule
CD59 分子靶点综述
CD59 也被称为保护素,在所有人类淋巴细胞、单核细胞、粒细胞和红细胞上均有表达。这种蛋白也在非造血细胞上表达,包括内皮细胞和神经元。CD59 与 CD2 相互作用,调节 T 细胞粘附,并在 T 细胞活化中发挥作用。最后,在系统性红斑狼疮(SLE)患者中观察到 CD55和 CD59 在人外周血细胞上的表达改变。
人 Human CD59 分子靶点信息
- 分子名:CD59, CD59 molecule (CD59 blood group)
- 别称:
- 16.3A5
- 1F5
- 1F5 antigen
- 20 kDa homologous restriction factor
- cd59 antigen
- CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
- CD59 blood group antigen
- CD59 glycoprotein
- CD59 molecule
- EJ16
- EJ30
- EL32
- FLJ38134
- FLJ92039
- G344
- HRF-20
- HRF20
- human leukocyte antigen MIC11
- Ly-6-like protein
- lymphocytic antigen CD59/MEM43
- MAC-IP
- MACIF
- MEM43
- MEM43 antigen
- membrane attack complex (MAC) inhibition factor
- membrane attack complex inhibition factor
- membrane inhibitor of reactive lysis
- MGC2354
- MIC11
- MIN1
- MIN2
- MIN3
- MIRL
- MSK21
- p18-20
- protectin
- surface anitgen recognized by monoclonal antibody 16.3A5
- T cell-activating protein
- 基因序列:NCBI_Gene: 966
- 蛋白序列:UniProtKB: P13987
人 Human CD59靶点分子功能(预测)
Predicted to enable complement binding activity. Acts upstream of or within regulation of complement activation and regulation of complement-dependent cytotoxicity. Located in cell surface. Is anchored component of external side of plasma membrane. Implicated in colorectal carcinoma and ovarian cancer. Biomarker of breast carcinoma; endometrial cancer; and ovarian cancer.