AT101

Annexin V-FITC/PI Apoptosis Kit（细胞凋亡试剂盒-适用贴壁细胞 除C6流式细胞仪以外的流式细胞仪）

¥860.00 – ¥1,510.00

在售SKU:70-AT101-100, 70-AT101-60, 70-AT101-30, 凋亡, 细胞凋亡, 凋亡试剂盒, 细胞凋亡试剂盒, 凋亡检测, 细胞凋亡检测, 凋亡检测试剂盒, 细胞凋亡检测试剂盒, Annexin V, Annexin, Apoptosis, 贴壁, 贴壁细胞, C6, C6细胞仪

产品简介

Annexin V(或 Annexin A5)为胞内蛋白膜联蛋白家族成员，以钙依赖的方式与磷脂酰丝氨酸(PS)结合。PS 存在于正常细胞浆膜的内层，但在凋亡早期，膜不对称性丧失，PS易位至细胞表面。荧光标记的 Annexin V 可与之特异性结合，表明该细胞为凋亡细胞。

Accutase是一种天然的酶，兼具蛋白水解酶和胶原酶的活性。但它比胰酶和胶原酶更有效，使用浓度更低，使之毒性更小、更温和。因此对细胞的损伤更小，可减少因消化处理带来的假阳性。即便长时间消化，也可保持90%以上的细胞活力。适合于各种贴壁细胞、胚胎和神经元干细胞等较敏感的细胞的消化。

产品特点

  • 操作简便，15分钟即可完成染色；
  • 分群清晰，结果稳定可靠；
  • 独家搭配阳性质控液，补偿调节不再困难；
  • 提供Accutase Enzyme，适用于贴壁细胞。

结果示例

试剂盒组分

引用文献统计

该产品被引用的文献总数为：1165

凋亡试剂盒操作常见问题

流式三要素之一 | 样本篇

流式三要素之一 | 样本篇 

蛇年第一课|小科带你回顾凋亡实验及其检测要点

蛇年第一课|小科带你回顾凋亡实验及其检测要点 

流式细胞术—FAQ（二）

流式细胞术—FAQ（二） 

流式细胞术—FAQ（一）

流式细胞术—FAQ（一） 

专利｜一种检验凋亡试剂真假的专利

专利｜一种检验凋亡试剂真假的专利 

流式实验中不可或缺的试剂—辅助试剂

流式实验中不可或缺的试剂—辅助试剂 

Accutase酶：凋亡检测最佳辅助

Accutase酶：凋亡检测最佳辅助 

论文分享 | 联科凋亡试剂助力巨噬细胞机理研究

论文分享 | 联科凋亡试剂助力巨噬细胞机理研究 

流式系列一 | 凋亡常见问题集合

流式系列一 | 凋亡常见问题集合 

你了解细胞凋亡及其检测的要点吗？

你了解细胞凋亡及其检测的要点吗？ 

细胞凋亡的主要途径及其机理

细胞凋亡的主要途径及其机理 

【流式细胞术】细胞凋亡数据分析技巧讲义

【流式细胞术】细胞凋亡数据分析技巧讲义 

查看更多凋亡试剂盒操作步骤技术文章

引用文献

文章目录[隐藏]


  1. Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β 

  2. The diagnostic value of has_circ_0006423 in non-small cell lung cancer and its role as a tumor suppressor gene that sponges miR-492. 

  3. A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy 

  4. Declined placental PLAC1 expression is involved in preeclampsia 

  5. Polymer micelle-based combination therapy of paclitaxel and resveratrol with enhanced and selective antitumor activity 

  6. A cold-water polysaccharide-protein complex from Grifola frondosa exhibited antiproliferative activity via mitochondrial apoptotic and Fas/FasL pathways in HepG2 cells 

  7. Hes1 is upregulated by ischemic postconditioning and contributes to cardioprotection 

  8. Chinese Herbal Medicine Suyin Detoxification Granule Inhibits Pyroptosis and Epithelial-Mesenchymal Transition by Downregulating MAVS/NLRP3 to Alleviate Renal Injury 

  9. Gambogenic acid induces apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells 

  10. Overexpression of ATAD2 indicates Poor Prognosis in Oral Squamous Cell Carcinoma 

  11. Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3 

  12. The role of miR-431-5p in regulating pulmonary surfactant expression in vitro 

  13. Increased Thioredoxin-1 Expression Promotes Cancer Progression and Predicts Poor Prognosis in Patients with Gastric Cancer 

  14. Fibroblast transdifferentiation promotes conversion of M1 macrophages and replenishment of cardiac resident macrophages following cardiac injury in mice 

  15. Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer 

  16. Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways 

  17. Aconiti Lateralis Radix Praeparata lipid-soluble alkaloids alleviates IL-1β-induced inflammation of human fibroblast-like synoviocytes in rheumatoid arthritis by inhibiting NF-κB and MAPKs signaling pathways and inducing apoptosis 

  18. S100P is Overexpressed in Squamous Cell and Adenosquamous Carcinoma Subtypes of Endometrial Cancer and Promotes Cancer Cell Proliferation and Invasion 

  19. Exosomes derived from miR-126-3p-overexpressing synovial fibroblasts suppress chondrocyte inflammation and cartilage degradation in a rat model of osteoarthritis 

  20. Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes 

  21. Retinoic acid receptor gamma is required for proliferation of pancreatic cancer cells 

  22. Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway 

  23. Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin‑angiotensin system 

  24. Preclinical efficacy and involvement of mTOR signaling in the mechanism of Orf virus against nasopharyngeal carcinoma cells 

  25. miR-182 selectively targets HOXA10 in goat endometrial epithelium cells in vitro 

  26. Immunomodulatory effect of thymopentin on lymphocytes from supramammary lymph nodes of dairy cows 

  27. Pinin promotes tumor progression via activating CREB through PI3K/AKT and ERK/MAPK pathway in prostate cancer 

  28. Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B 

  29. HN1L is essential for cell growth and survival during nucleopolyhedrovirus infection in silkworm, Bombyx mori 

  30. Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70 

  31. LncRNA882 regulates leukemia inhibitory factor (LIF) by sponging miR-15b in the endometrial epithelium cells of dairy goat 

  32. Blockade of the mTOR signaling pathway with rapamycin ameliorates aristolochic acid nephropathy 

  33. Characterization and anti-uterine tumor effect of extract from Prunella vulgaris L. 

  34. Therapeutic potential of transplanted placental mesenchymal stem cells in treating Chinese miniature pigs with acute liver failure 

  35. The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression 

  36. Long non-coding RNA MACC1-AS1 promoted pancreatic carcinoma progression through activation of PAX8/NOTCH1 signaling pathway 

  37. MiR-206 suppresses the deterioration of intrahepatic cholangiocarcinoma and promotes sensitivity to chemotherapy by inhibiting interactions with stromal CAFs 

  38. Alkaloid Dimers Isolated from Thalictrum baicalense Have Antitumor Activities 

  39. Effect of ximenynic acid on cell cycle arrest and apoptosis and COX-1 in HepG2 cells 

  40. Cuprous oxide nanoparticles trigger ER stress-induced apoptosis by regulating copper trafficking and overcoming resistance to sunitinib therapy in renal cancer 

  41. N7-methylguanosine tRNA modification promotes tumorigenesis and chemoresistance through WNT/β-catenin pathway in nasopharyngeal carcinoma 

  42. Impact of low-intensity pulsed ultrasound on transcription and metabolite compositions in proliferation and functionalization of human adipose-derived mesenchymal stromal cells. 

  43. TRIP13 interference inhibits the proliferation and metastasis of thyroid cancer cells through regulating TTC5/p53 pathway and epithelial-mesenchymal transition related genes expression 

  44. The Combined Use of Orf Virus and PAK4 Inhibitor Exerts Anti-tumor Effect in Breast Cancer 

  45. Bone marrow mesenchymal stromal cells affect the cell cycle arrest effect of genotoxic agents on acute lymphocytic leukemia cells via p21 down-regulation 

  46. Polystyrene micro- and nano-particle coexposure injures fetal thalamus by inducing ROS-mediated cell apoptosis 

  47. Curcusone C induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2 

  48. The effects of SAHA on radiosensitivity in pancreatic cancer cells by inducing apoptosis and targeting RAD51 

  49. miR-148a-3p regulates proliferation and apoptosis of bovine muscle cells by targeting KLF6 

  50. ΔFosB regulates rosiglitazone-induced milk fat synthesis and cell survival 

  51. A MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer 

  52. Puerarin inhibits proliferation and induces apoptosis in human glioblastoma cell lines 

  53. PMEPA1 induces EMT via a non-canonical TGF-β signalling in colorectal cancer 

  54. Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage 

  55. Design, synthesis, and bioactivity study on Lissodendrins B derivatives as PARP1 inhibitor 

  56. Immunosuppressive activity of pogostone on T cells: Blocking proliferation via S phase arrest 

  57. The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer 

  58. Baicalein inhibits the growth of oral squamous cell carcinoma cells by downregulating the expression of transcription factor Sp1 

  59. miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development 

  60. circFGFR4 Promotes Differentiation of Myoblasts via Binding miR-107 to Relieve Its Inhibition of Wnt3a 

  61. MiR-520d-3p antitumor activity in human breast cancer via post-transcriptional regulation of spindle and kinetochore associated 2 expression 

  62. The novel long noncoding RNA u50535 promotes colorectal cancer growth and metastasis by regulating CCL20 

  63. Long non‑coding RNA maternally expressed gene 3 affects cell proliferation, apoptosis and migration by targeting the microRNA‑9‑5p/midkine axis and activating the phosphoinositide‑dependent kinase/AKT pathway in hepatocellular carcinoma 

  64. Long non-coding RNA AC026166.2-001 inhibits cell proliferation and migration in laryngeal squamous cell carcinoma by regulating the miR-24-3p/p27 axis 

  65. miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression 

  66. SQLE Promotes Differentiation and Apoptosis of Bovine Skeletal Muscle-Derived Mesenchymal Stem Cells 

  67. MiR-449a regulates caprine endometrial stromal cell apoptosis and endometrial receptivity 

  68. A novel core-shell nanofiber drug delivery system intended for the synergistic treatment of melanoma 

  69. Survivin-targeted drug screening platform identifies a matrine derivative WM-127 as a potential therapeutics against hepatocellular carcinoma 

  70. Targeting the LSD1-G9a-ER Stress Pathway as a Novel Therapeutic Strategy for Esophageal Squamous Cell Carcinoma. 

  71. NMI promotes cell proliferation through TGFβ/Smad pathway by upregulating STAT1 in colorectal cancer 

  72. CircFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a 

  73. Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p 

  74. CircRNA-9119 regulates the expression of prostaglandin-endoperoxide synthase 2 (PTGS2) by sponging miR-26a in the endometrial epithelial cells of dairy goat 

  75. MiR-93 suppresses tumorigenesis and enhances chemosensitivity of breast cancer via dual targeting E2F1 and CCND1 

  76. Bouchardatine suppresses rectal cancer in mice by disrupting its metabolic pathways via activating the SIRT1-PGC-1α-UCP2 axis 

  77. Bone morphogenetic protein 4 regulates immortalized chicken preadipocyte proliferation by promoting G1/S cell cycle progression 

  78. Glucose-regulated protein 78 modulates cell growth, epithelial–mesenchymal transition, and oxidative stress in the hyperplastic prostate 

  79. Sequence and expression regulation of the BCL2L2 gene in pigs 

  80. Candida glabrata induced infection of rat tracheal epithelial cells is mediated by TLR-2 induced activation of NF-κB 

  81. ACSS2/AMPK/PCNA pathway‑driven proliferation and chemoresistance of esophageal squamous carcinoma cells under nutrient stress 

  82. Role of bta-miR-204 in the regulation of adipocyte proliferation, differentiation, and apoptosis 

  83. Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling 

  84. Identification of Monobenzone as a Novel Potential Anti-Acute Myeloid Leukaemia Agent That Inhibits RNR and Suppresses Tumour Growth in Mouse Xenograft Model 

  85. Combination Treatment With Inhibitors of ERK and Autophagy Enhances Antitumor Activity of Betulinic Acid in Non–small-Cell Lung Cancer In Vivo and In Vitro 

  86. 8‑Gingerol regulates colorectal cancer cell proliferation and migration through the EGFR/STAT/ERK pathway 

  87. Synergistic effect of a retinoid X receptor-selective ligand bexarotene and docetaxel in prostate cancer 

  88. Hsa_circ_0043278 Inhibits Tumorigenesis and is Downregulated in Colorectal Cancer 

  89. Berbamine Suppresses the Growth of Gastric Cancer Cells by Inactivating the BRD4/c-MYC Signaling Pathway 

  90. PLCE1 as a diagnostic and prognostic biomarker by promoting the growth and progression of oral squamous cell carcinoma 

  91. LncRNA DPP10-AS1 promotes malignant processes through epigenetically activating its cognate gene DPP10 and predicts poor prognosis in lung cancer patients 

  92. The Core Mechanism of Yiqi Yangjing Decoction Inhibiting Nonsmall-Cell Lung Cancer 

  93. High-Dose Vitamin C Tends to Kill Colorectal Cancer with High MALAT1 Expression 

  94. Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms 

  95. Interaction of Quindoline derivative with telomeric repeat–containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2 

  96. Inhibition of AMPK/PFKFB3 mediated glycolysis synergizes with penfluridol to suppress gallbladder cancer growth 

  97. Long non-coding RNA MIR4435-1HG promotes cancer growth in clear cell renal cell carcinoma 

  98. N6-methyladenosine modification of TGM2 mRNA contributes to the inhibitory activity of sarsasapogenin in rheumatoid arthritis fibroblast-like synoviocytes 

  99. Aberrant translation regulated by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives head and neck squamous cell carcinoma progression 

  100. Upregulated bone morphogenetic protein 5 enhances proliferation and epithelial–mesenchymal transition process in benign prostatic hyperplasia via BMP/Smad signaling pathway 

  101. Long non-coding RNA LINC00662 promotes proliferation and migration in oral squamous cell carcinoma 

  102. Circ-UBR1 facilitates proliferation, metastasis, and inhibits apoptosis in breast cancer by regulating the miR-1299/CCND1 axis 

  103. m6A Methylases Regulate Myoblast Proliferation, Apoptosis and Differentiation 

  104. Novel isatin-based hybrids as potential anti-rheumatoid arthritis drug candidates: Synthesis and biological evaluation 

  105. Effects of PLIN1 Gene Knockout on the Proliferation, Apoptosis, Differentiation and Lipolysis of Chicken Preadipocytes 

  106. Melatonin inhibits embryonic rat H9c2 cells growth through induction of apoptosis and cell cycle arrest via PI3K-AKT signaling pathway 

  107. A dual-targeted molecular therapy of PP242 and cetuximab plays an anti-tumor effect through EGFR downstream signaling pathways in colorectal cancer 

  108. Knockdown of DUXAP10 inhibits proliferation and promotes apoptosis in bladder cancer cells via PI3K/Akt/mTOR signaling pathway 

  109. Oridonin inhibits BxPC-3 cell growth through cell apoptosis 

  110. Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3′-UTRs of RAC2/BCL2L1 and the coding region of PAK4 

  111. Sinularin exerts anti-tumor effects against human renal cancer cells relies on the generation of ROS 

  112. 2-phenylethynesulfonamide inhibits growth of oral squamous cell carcinoma cells by blocking the function of heat shock protein 70 

  113. C21 Fraction Refined from Marsdenia tenacissima-Induced Apoptosis is Enhanced by Suppression of Autophagy in Human Gastric Cell Lines 

  114. Reversibility of hAT-MSCs phenotypic and metabolic changes after exposure to and withdrawal from HCC-conditioned medium through regulation of the ROS/MAPK/HIF-1α signaling pathway 

  115. Long Non-Coding RNA XLOC_006753 Promotes the Development of Multidrug Resistance in Gastric Cancer Cells Through the PI3K/AKT/mTOR Signaling Pathway 

  116. Implication of myeloid differentiation factor 88 inhibitor TJ-M2010-5 for therapeutic intervention of hepatocellular carcinoma 

  117. TJ-M2010-5, a novel CNS drug candidate, attenuates acute cerebral ischemia-reperfusion injury through the MyD88/NF-κB and ERK pathway 

  118. Folic acid modified UiO-66 nano drug carrier for combination therapy 

  119. Independent Association of Thyroid Dysfunction and Inflammation Predicts Adverse Events in Patients with Heart Failure via Promoting Cell Death 

  120. A pH-responsive chiral mesoporous silica nanoparticles for delivery of doxorubicin in tumor-targeted therapy 

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2
Li S J, Sun Z Y, Chen T, et al. The role of miR-431-5p in regulating pulmonary surfactant expression in vitro[J]. Cellular & Molecular Biology Letters, 2019, 24(1): 1689-1392 (IF:4.302)

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3
Ma C X, Fu Z Y, Guo H, et al. The effects of Radix Angelica Sinensis and Radix Hedysari ultrafiltration extract on X-irradiation-induced myocardial fibrosis in rats[J]. Biomedicine & Pharmacotherapy, 2019, 112: 108596 (IF:3.457)

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