生命科学与医学最新热点方向排名

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日前,汤森路透首次发布了前沿研究、科研管理与科学政策制定的相关报告:《2013研究前沿:科学与社科领域的百强研究》(Research Fronts 2013: 100 Top Ranked Specialties in the Sciences and Social Sciences)。报告中列出了当前十大前沿研究领域,以及每个领域中排名前十的重点研究。这次公布的研究,也可能成为2013年度科学与社科领域的重点。

该报告对2007年至2012年高引用率的研究论文,以及发表在核心期刊和基础期刊上的文章进行分析后发现,科学与社会科学领域的前沿研究主要涉及以下十大领域:

农业、植物与动物科学(Agriculture, Plant and Animal Sciences)

生态学与环境科学(Ecology and Environmental Sciences)

地球科学(Geosciences)

临床医学(Clinical Medicine)

生物科学(Biological Sciences)

化学与材料科学(Chemistry and Materials Science)

物理学(Physics)

天文学与天体物理学(Astronomy and Astrophysics)

数学、计算科学与工程学(Mathematics, Computer Science and Engineering)

经济学、心理学和其他社会科学(Economics, Psychology and Other Social Sciences)

研究人员表示,对科研领域进行趋势分析能让研究人员、科研资助者和机构管理人员对当前的科研发展有一个整体认识,帮助他们在科研精力投入、科研资金和资源分配等方面做出更好的决策。

生物科学(Biological Sciences)领域中排名前十的重点研究如下:

RANK research fronts core
papers
citations mean year of
core papers
1  DNA methylation analysis and missing heritability 25 3,153 2011
2  Toxicity of amyloid beta (Aβ) oligomers in Alzheimer’s disease 45 2,588 2010.6
3  Differentiation and function of follicular helper CD4 T cells (TFH) 38 2760 2010.5
4  Human beta(2) adrenergic G-protein-coupled receptors (GPCRs) 44 6261 2010.4
5  Linear ubiquitin chain assembly complex and activation of nuclear factor-κB (NF-κB) 43 3,749 2010.4
6  Lgr5 receptor-expressing intestinal stem cells 23 2,699 2010.3
7  TET mutations, reduction of 5-hydroxymethylcytosine (5hmC), and malignancy 45 6,112 2010.2
8 Inhibition of TO R (Target Of Rapamycin) signaling, increased lifespan,
and diseases of aging
30 3,152 2010.1
9  HIV-1 Vpu and Vpx proteins and restriction factors SAMHD1 and BST -2/Tetherin 48 3,760 2009.9
10  Mitochondrial sirtuins and regulation of metabolism 32 3,395 2009.9

农业、植物与动物科学(Agriculture, Plant and Animal Sciences)领域中排名前十的重点研究如下:
位列三甲的分别为: DNA甲基化与丢失遗传性研究、阿尔茨海默症的β淀粉样蛋白(Aβ)、滤泡辅助性CD4 T细胞(TFH)的分化和功能。

RANK

 research fronts

core
papers

citations

mean year of
core papers

1

 Impact of climate change on food crops

32

1537

2010

2

Comprehensive classification of fungi based on molecular evolutionary analysis

18

1374

2010

3

Arabidopsis chloroplast RnA editing

46

2578

2009.9

4

Jasmonate biosynthesis and signaling

33

2548

2009.9

5

oomycete RXlR effectors and suppression of plant immunity

47

2340

2009.7

6

Angiosperm phylogeny group classification

34

2259

2009.7

7

methicillin-resistant Staphylococcus aureus (mRsA) in livestock

17

1071

2009.7

8

genomic selection and estimated breeding values

39

2281

2009.6

9

honey bee colony collapse disorder and Nosema ceranae

30

1718

2009.6

10

insect resistance to transgenic crops producing bt (Bacillus thuringiensis) toxins for pest control

22

1134

2009.6

生态学与环境科学(Ecology and Environmental Sciences)领域中排名前十的重点研究如下:

RANK

research fronts

core
papers

citations

mean year of
core papers

1

 ocean acidification and marine ecosystems

45

3653

2009.6

2

 biodiversity and functional ecosystems

43

3139

2009.5

3

 mangrove forests and climate change

16

1121

2009.5

4

 models and impacts of land-use change

18

2318

2009.4

5

 biochar amendment techniques and effects

41

2300

2009.4

6

 Adaptive evolution in invasive species and approximate bayesian computation

19

1255

2009.4

 Chytridiomycosis and large-scale amphibian population extinctions

13

1003

2009.3

8

 Pharmaceutical residues in environmental water and wastewater

50

3815

2009.1

9

 Community ecology and phylogenetic comparative biology

20

1,799

2009.1

10

 Climate warming, altered thermal niches, and species impact

14

1,244

2009.1

临床医学(Clinical Medicine)领域中排名前十的重点研究如下:

RANK

 research fronts

core
papers

citations

mean year of
core papers

1

 transcatheter aortic valve implantation

50

2818

2011

2

 Atypical hemolytic uremic syndrome and complement activation

36

1939

2010.6

3

 Acquired bRAf inhibitor resistance in metastatic melanoma

36

4777

2010.5

 idiopathic pulmonary fibrosis and randomized placebo-controlled drug  trials

38

2269

2010.5

5

 Pathology and treatment of nonalcoholic fatty liver disease

34

1978

2010.5

6

 Chemotherapy with and without bevacizumab for heR2-negative  breast cancer

14

1909

2010.5

7

 brentuximab vedotin for refractory and relapsed hodgkin’s lymphoma

23

2001

2010.4

8

 il28b polymorphisms and treatment response in hepatitis C patients

47

5172

2010.3

 Anaplastic lymphoma kinase (AlK) inhibition in non-small cell lung cancer

46

3716

2010.3

10

 global, national, and regional assessments of maternal, newborn, and child health

42

2640

2010.3