Human IFN-γ Standard (人γ干扰素标准品)

IFNG 分子靶点信息概述

• 分子名：IFNG, interferon gamma
• 基因家族：Interferons

IFNG 分子靶点综述

IFN-γ主要由Th1型细胞产生，属于II型细胞因子中干扰素家族中的一员，是一类分泌型糖蛋白，由143个氨基酸组成，相对分子质量是16942。IFN-γ主要由活化的T细胞和NK细胞产生，具有调节机体免疫状态，介导细胞免疫，加强受体介导的吞噬功能，增强巨噬细胞和中性粒细胞的杀伤活性，具有抗病毒感染及抗肿瘤等生物学活性。

人 Human IFNG 分子靶点信息

• 分子名：IFNG, interferon gamma
• 别称：
  • IFG
  • IFI
  • IFN-gamma
  • IMD69
  • immune interferon
  • interferon, gamma
• 基因序列：NCBI_Gene: 3458
• 蛋白序列：UniProtKB: P01579

人 Human IFNG靶点分子功能（预测）

Predicted to enable cytokine activity. Involved in several processes, including positive regulation of cell death; positive regulation of cell differentiation; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including positive regulation of gene expression; positive regulation of protein phosphorylation; and response to virus. Located in extracellular region. Implicated in several diseases, including ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; factor VIII deficiency; and leukemia (multiple). Biomarker of several diseases, including acute retinal necrosis syndrome; allergic rhinitis; autoimmune disease (multiple); nephritis (multiple); and otitis media (multiple).