文章目录[隐藏]
- MMP9 分子靶点信息概述
- MMP9 分子靶点综述
- MMP9, matrix metallopeptidase 9 分子靶点种属信息
- MMP9 分子产品列表
- Rat Total MMP-9 Standard (大鼠总基质金属蛋白酶9 标准品)
- Rat Total MMP-9 ELISA Kit检测试剂盒(酶联免疫吸附法)
- Mouse Total MMP-9 ELISA Kit检测试剂盒(酶联免疫吸附法)
- Mouse Total MMP-9 Standard (小鼠总基质金属蛋白酶9 标准品)
- Human MMP-9 ELISA Kit检测试剂盒(酶联免疫吸附法)
- Human MMP-9 Standard (人基质金属蛋白酶9标准品)
- MMP9 分子靶点最新资讯
MMP9 分子靶点信息概述
- 分子名:MMP9, matrix metallopeptidase 9
- 基因家族:M10 matrix metallopeptidases
- 曾用名:CLG4B
- 全称:matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
MMP9 分子靶点综述
基质金属蛋白酶9(MMP-9),又名92kDaIV型胶原酶、92kDa明胶酶或者明胶酶B,是一类属于锌-金属蛋白酶家族的酶。MMP-9参与正常生理过程(如胚胎发育、繁殖、血管形成、骨骼发育、伤口愈细胞迁移、学习和记忆)和病理过程(如关节炎、脑出血和肿瘤转移)的细胞外基质降解。MMP-9和弹性蛋白酶似乎是中性粒细胞迁移通过基底膜的调节因子。MMP-9在血管和新生血管形成中起重要作用。它在人类呼吸道上皮愈合过程中被显著上调,并被发现与许多病理过程相关,如癌症、免疫和心血管疾病。在类风湿性关节炎、局灶性脑缺血案例中可发现MMP-9的水平是升高的。它的水平随着特发性房颤的发展而增加。
MMP9, matrix metallopeptidase 9 分子靶点种属信息
人 Human MMP9 分子靶点信息
- 分子名:MMP9, matrix metallopeptidase 9
- 别称:
- 92 kDa gelatinase
- 92 kDa type IV collagenase
- CLG4B
- GELB
- macrophage gelatinase
- MANDP2
- matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
- matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
- matrix metalloproteinase-9
- MMP-9
- type V collagenase
- 基因序列:NCBI_Gene: 4318
- 蛋白序列:UniProtKB: P14780
人 Human MMP9靶点分子功能(预测)
Enables identical protein binding activity; metalloendopeptidase activity; and serine-type endopeptidase activity. Involved in several processes, including cellular response to UV-A; negative regulation of apoptotic signaling pathway; and positive regulation of keratinocyte migration. Located in extracellular space. Implicated in several diseases, including Down syndrome; anodontia; artery disease (multiple); autoimmune disease (multiple); and chronic obstructive pulmonary disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); brain disease (multiple); carcinoma (multiple); and lung disease (multiple).
小鼠 Mouse Mmp9 分子靶点信息
- 分子名:Mmp9, matrix metallopeptidase 9
- 别称:
- AW743869
- B/MMP9
- Clg4b
- collagenase IVB, basement membrane, 92 kDa
- expressed sequence AW743869
- Gel B
- Gelatinase B
- gelatinase B
- MMP-9
- 基因序列:NCBI_Gene: 17395
- 蛋白序列:
小鼠 Mouse Mmp9 靶点分子功能(预测)
Enables metalloendopeptidase activity. Involved in negative regulation of epithelial cell differentiation involved in kidney development and response to amyloid-beta. Acts upstream of or within several processes, including collagen catabolic process; embryo implantation; and extracellular matrix organization. Located in collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; limb mesenchyme; and skeleton. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; anodontia; artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Orthologous to human MMP9 (matrix metallopeptidase 9).
大鼠 Rat Mmp9 分子靶点信息
- 分子名:Mmp9, matrix metallopeptidase 9
- 别称:
- 92 kDa gelatinase
- 92 kDa type IV collagenase
- 92-kDa type IV collagenase
- gelatinase B
- GELB
- matrix metalloproteinase 9 (gelatinase B 92-kDa type IV collagenase)
- matrix metalloproteinase 9 (gelatinase B, 92-kDa type IV collagenase)
- matrix metalloproteinase-9
- MMP-9
- 基因序列:NCBI_Gene: 81687
- 蛋白序列:
大鼠 Rat Mmp9 靶点分子功能(预测)
Enables fibronectin binding activity and metallopeptidase activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to cytokine stimulus; and cellular response to iron(III) ion. Located in extracellular space. Part of protein-containing complex. Used to study artery disease (multiple); brain ischemia (multiple); congestive heart failure; glomerulosclerosis; and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); chronic obstructive pulmonary disease (multiple); glucose metabolism disease (multiple); and kidney disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; anodontia; artery disease (multiple); autoimmune disease (multiple); and chronic obstructive pulmonary disease (multiple). Orthologous to human MMP9 (matrix metallopeptidase 9).
MMP9 分子产品列表
-
- EK3M09S
- ELISA标准品
Rat Total MMP-9 Standard (大鼠总基质金属蛋白酶9 标准品)
- ¥280.00
-
- EK3M09
- ELISA试剂盒
Rat Total MMP-9 ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,900.00 – ¥3,200.00
-
- EK2M09
- ELISA试剂盒
Mouse Total MMP-9 ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥2,000.00 – ¥3,400.00
-
- EK2M09S
- ELISA标准品
Mouse Total MMP-9 Standard (小鼠总基质金属蛋白酶9 标准品)
- ¥280.00
-
- EK1M09
- ELISA试剂盒
Human MMP-9 ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥2,650.00
-
- EK1M09S
- ELISA标准品
Human MMP-9 Standard (人基质金属蛋白酶9标准品)
- ¥280.00