Human C-Reactive Protein ELISA Kit检测试剂盒(酶联免疫吸附法)
¥1,600.00 – ¥2,650.00
在售SKU:70-EK194-48, 70-EK194-96, EK194
- 分子靶点:CRP
- 种属:人
- 样本类型:血清、血浆、细胞培养上清及其他生物学样本
- 检测样本体积:血清、血浆样本10μL
- 灵敏度:0.44pg/mL
- 检测范围:62.5-4000pg/mL
- 回收率:93%-107%
ELISA试剂盒详细信息
商品名 | 人C反应蛋白酶联免疫检测试剂盒 |
---|---|
种属 | 人 |
靶点 | CRP |
检测方法 | 双抗体夹心法 |
检测样本类型 | 血清、血浆、细胞培养上清及其他生物学样本 |
检测样本体积 | 血清、血浆样本10μL |
灵敏度 | 0.44pg/mL |
线性范围 | 62.5-4000pg/mL |
精密度 | 板内变异系数:2.9%-5.5%;板间变异系数:3.0%-5.8% |
回收率 | 93%-107% |
平均回收率 | 100% |
板式 | 96孔板,可拆 |
保存条件 | 2-8℃保存。已拆开:标准品-20℃保存,其它4℃。 |
运输条件 | 2-8℃冰袋运输 |
检测原理 | 本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人CRP抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的CRP与固相抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后,加入显色底物TMB,避光显色。颜色反应的深浅与样本中CRP的浓度成正比。加入终止液终止反应,在450nm波长(参考波长570 - 630nm)测定吸光度值。 |
分子信息
CRP 分子靶点信息概述
- 分子名:CRP, C-reactive protein
- 基因家族:Short pentraxins
- 别名:PTX1
- 全称:pentraxin 1; C-reactive protein, pentraxin-related
CRP 分子靶点综述
C-反应蛋白(CRP)是在血浆中发现的一种环状、五聚体蛋白。肝脏对巨噬细胞和脂肪细胞释放的因子产生应答后可合成CRP。CRP是一种肝源性的急性蛋白,在巨噬细胞和T细胞分泌白介素6后增加,其生理作用是与死细胞或濒死细胞(和某些类型的细菌)表面的溶血磷脂胆碱结合,以通过C1Q复合物来激活补体系统。它与C-肽(胰岛素)或蛋白C(血凝)不相关。CRP通常作为炎症标志物,当机体受到炎症感染时,CRP水平会上升。最近的研究表明,患者具有较高基础水平的CRP,通常伴随着一个较高糖尿病、高血压和心血管疾病的发生率。
人 Human CRP 分子靶点信息
- 分子名:CRP, C-reactive protein
- 别称:
- C-reactive protein, pentraxin-related
- c-reactive protein, petaxin related
- MGC149895
- MGC88244
- pentraxin 1
- PTX1
- 基因序列:NCBI_Gene: 1401
- 蛋白序列:UniProtKB: P02741
人 Human CRP靶点分子功能(预测)
Enables several functions, including complement component C1q complex binding activity; low-density lipoprotein particle binding activity; and low-density lipoprotein particle receptor binding activity. Involved in several processes, including negative regulation of macrophage derived foam cell differentiation; positive regulation of superoxide anion generation; and regulation of gene expression. Acts upstream of or within vasoconstriction. Located in extracellular space. Implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); macular degeneration (multiple); middle cerebral artery infarction; and nephritis (multiple). Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); autoimmune disease (multiple); eye disease (multiple); and lung disease (multiple).
引用文献统计
该产品被引用的文献总数为:9
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影响因子:5.846刊物:Frontiers in Cardiovascular Medicine发表日期:2022/7/22 - Effects of continuous negative pressure suction combined with autologous platelet-rich gel on the levels of CRP, IL-6, wound healing and length of stay in clients with diabetic foot
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影响因子:6.1刊物:Journal of Translational Medicine发表日期:2024-02-17 - BMI-specific inflammatory response to phthalate exposure in early pregnancy: findings from the TMCHESC study
影响因子:5.8刊物:ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH发表日期:2023-11-20 - Analysis of Therapeutic Effect and Influencing Factors of Ultrasound-Guided Radiofrequency Ablation in the Treatment of Papillary Thyroid Microcarcinoma
影响因子:2.3刊物:JOURNAL OF ULTRASOUND IN MEDICINE发表日期:2023-03-07 - Establishment of a Rat Model of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (Cp/Cpps) Induced by Immunization with a Novel Peptide T2
刊物:Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 91, 687-692 (2017)