S100A6 靶点信息

S100A6 分子靶点信息概述

  • 分子名：S100A6, S100 calcium binding protein A6
  • 基因家族：S100 calcium binding proteins; EF-hand domain containing
  • 别名：2A9; PRA; CABP
  • 曾用名：CACY
  • 全称：calcyclin; S100 calcium-binding protein A6 (calcyclin)

S100A6 分子靶点综述

S100蛋白是一类存在于脊椎动物中的低分子量蛋白质家族，其典型特征为具有两个EF手型钙结合结构域。该家族至少包含21种不同成员，其名称源于该类蛋白质在中性pH条件下能100%溶于硫酸铵溶液的特性。多数S100蛋白通过二硫键连接形成同源二聚体，通常存在于神经嵴来源细胞、软骨细胞、巨噬细胞、树突状细胞等细胞中。S100蛋白在细胞内外的多种功能活动中发挥作用，包括调节蛋白质磷酸化、转录因子活性、细胞骨架成分动态变化、酶活性、细胞生长与分化以及炎症反应等。S100A6（S100钙结合蛋白A6）作为该家族成员，参与催乳素分泌和胞吐作用过程。研究显示，S100A6的染色体易位和表达异常与黑色素瘤的发生发展密切相关。

S100A6, S100 calcium binding protein A6 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human S100A6 分子靶点信息

  • 分子名：S100A6, S100 calcium binding protein A6
  • 别称：
    • 2A9
    • 5B10
    • CABP
    • CACY
    • calcyclin
    • growth factor-inducible protein 2A9
    • MLN 4
    • PRA
    • prolactin receptor-associated protein
    • protein S100-A6
    • s100 calcium binding protein a6 (calcyclin)
    • S100 calcium-binding protein A6 (calcyclin)
    • S10A6
  • 基因序列：NCBI_Gene: 6277
  • 蛋白序列：UniProtKB: P06703

人 Human S100A6 靶点分子功能（预测）

Enables several functions, including S100 protein binding activity; protein homodimerization activity; and tropomyosin binding activity. Predicted to be involved in cellular response to virus. Located in several cellular components, including cytoplasmic side of plasma membrane; perinuclear region of cytoplasm; and ruffle.

小鼠 Mouse S100a6 分子靶点信息

小鼠 Mouse S100a6 靶点分子功能（预测）

Enables calcium ion binding activity and zinc ion binding activity. Predicted to be involved in monoatomic ion transmembrane transport. Located in collagen-containing extracellular matrix. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and trophectoderm. Orthologous to human S100A6 (S100 calcium binding protein A6).

大鼠 Rat S100a6 分子靶点信息

  • 分子名：S100a6, S100 calcium binding protein A6
  • 别称：
    • calcium binding protein A6 (calcyclin)
    • calcyclin
    • prolactin receptor-associated protein
    • protein S100-A6
    • S100 calcium binding protein A6 (calcyclin)
    • S100 calcium-binding protein A6
  • 基因序列：NCBI_Gene: 85247
  • 蛋白序列：

大鼠 Rat S100a6 靶点分子功能（预测）

Enables calcium ion binding activity and monoatomic ion transmembrane transporter activity. Predicted to be involved in cellular response to virus. Predicted to be located in several cellular components, including cytoplasmic side of plasma membrane; nuclear envelope; and ruffle. Predicted to be active in nucleus and perinuclear region of cytoplasm. Orthologous to human S100A6 (S100 calcium binding protein A6).

S100A6 分子产品列表

S100A6 分子靶点最新资讯

不同疾病领域的 “科研路标”