NCAM1 靶点信息

NCAM1 分子靶点信息概述

  • 分子名：NCAM1, neural cell adhesion molecule 1
  • 基因家族：CD molecules; Fibronectin type III domain containing; I-set domain containing; Ig-like cell adhesion molecule family
  • 别名：NCAM; CD56

NCAM1 分子靶点综述

CD56也称为神经细胞黏着分子(Neural Cell Adhesion molecule, NCAM)、Leu-19或NKH1，是分子量为140 kD的跨膜糖蛋白。CD56表达于神经元，在神经细胞的同质粘附中发挥作用。在造血系统中，它表达于NK和NKT细胞，在细胞粘附中发挥作用。

NCAM1, neural cell adhesion molecule 1 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human NCAM1 分子靶点信息

  • 分子名：NCAM1, neural cell adhesion molecule 1
  • 别称：
    • antigen recognized by monoclonal antibody 5.1H11
    • CD56
    • MSK39
    • N-CAM-1
    • NCAM
    • NCAM-1
    • neural cell adhesion molecule, NCAM
  • 基因序列：NCBI_Gene: 4684
  • 蛋白序列：UniProtKB: P13591

人 Human NCAM1靶点分子功能（预测）

Predicted to enable virus receptor activity. Predicted to be involved in commissural neuron axon guidance; modulation of chemical synaptic transmission; and regulation of semaphorin-plexin signaling pathway. Predicted to act upstream of or within several processes, including homotypic cell-cell adhesion; positive regulation of calcium-mediated signaling; and regulation of exocyst assembly. Located in cytosol and external side of plasma membrane. Implicated in bipolar disorder; middle cerebral artery infarction; and pancreatic cancer. Biomarker of several diseases, including acute promyelocytic leukemia; brain glioblastoma multiforme; cholangiocarcinoma; insulinoma; and ovarian serous carcinoma.

小鼠 Mouse Ncam1 分子靶点信息

小鼠 Mouse Ncam1 靶点分子功能（预测）

Predicted to enable LRR domain binding activity and phosphatase binding activity. Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including homotypic cell-cell adhesion; positive regulation of calcium-mediated signaling; and regulation of exocyst assembly. Located in several cellular components, including external side of plasma membrane; growth cone; and neuronal cell body. Is expressed in several structures, including embryo mesenchyme; nervous system; sensory organ; skin; and urinary system. Human ortholog(s) of this gene implicated in bipolar disorder; middle cerebral artery infarction; and pancreatic cancer. Orthologous to human NCAM1 (neural cell adhesion molecule 1).

大鼠 Rat Ncam1 分子靶点信息

大鼠 Rat Ncam1 靶点分子功能（预测）

Enables enzyme binding activity. Involved in cellular response to hypoxia; flagellated sperm motility; and spermatogenesis. Located in cytoplasm. Orthologous to several human genes including MST1 (macrophage stimulating 1).

NCAM1 分子产品列表

NCAM1 分子靶点最新资讯