IL25 分子靶点信息概述

  • 分子名:IL25, interleukin 25
  • 基因家族:Interleukins
  • 别名:IL-25; IL-17E
  • 曾用名:IL17E
  • 全称:interleukin 17E

IL25 分子靶点综述

白细胞介素17E(IL-17E),又名IL-25,是IL-17家族中的一员,由2型辅助性T细胞(Th2)和肥大细胞分泌产生。它与IL-17序列相似,可诱导NF-κB活化,刺激IL-8的产生。IL-17E和IL-17B是细胞因子受体IL-17RB的配体。小鼠的研究表明,IL-17E可能是一种促炎性细胞因子,有利于Th2型免疫应答。IL-17E诱导多种组织中的其它细胞因子产生,包括IL-4、IL-5和IL-13,从而刺激嗜酸性粒细胞增多。该细胞因子是一种调控肠道免疫的重要分子,参与与胃肠道相关的慢性炎症。IL-17E可杀死某些类型的乳腺癌细胞。

IL25, interleukin 25 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human IL25 分子靶点信息

  • 分子名:IL25, interleukin 25
  • 别称:
    • IL-17E
    • IL-25
    • IL17E
    • interleukin 17E
    • interleukin-17E
    • interleukin-25
  • 基因序列:NCBI_Gene: 64806
  • 蛋白序列:UniProtKB: Q9H293

人 Human IL25靶点分子功能(预测)

Predicted to enable interleukin-17E receptor binding activity. Predicted to be involved in inflammatory response to antigenic stimulus and signal transduction. Predicted to act upstream of or within several processes, including eosinophil differentiation; response to fungus; and response to nematode. Predicted to be located in extracellular region. Biomarker of atopic dermatitis and psoriasis.

小鼠 Mouse Il25 分子靶点信息

小鼠 Mouse Il25 靶点分子功能(预测)

Enables cytokine activity. Acts upstream of or within several processes, including eosinophil differentiation; response to fungus; and response to nematode. Predicted to be located in extracellular space. Orthologous to human IL25 (interleukin 25).

大鼠 Rat Il25 分子靶点信息

大鼠 Rat Il25 靶点分子功能(预测)

Predicted to enable cytokine activity. Involved in inflammatory response to antigenic stimulus. Located in extracellular space. Biomarker of gastric ulcer. Orthologous to human IL25 (interleukin 25).

IL25 分子产品列表

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