FUT4 靶点信息

FUT4 分子靶点信息概述

  • 分子名：FUT4, fucosyltransferase 4
  • 基因家族：Fucosyltransferases; CD molecules
  • 别名：FUC-TIV
  • 曾用名：CD15; FCT3A; ELFT
  • 全称：galactoside 3-L-fucosyltransferase; alpha (1,3) fucosyltransferase, myeloid-specific; ELAM ligand fucosyltransferase

FUT4 分子靶点综述

CD15 是一种 220 kDa 碳水化合物，又称 SSEA-1，Lewis3-fucosyl-N-acetyllactosamine(3-FAL)。CD15 在大多数粒细胞和单核细胞上表达，淋巴细胞上不表达。它参与细胞粘附、趋化和吞噬。

FUT4, fucosyltransferase 4 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human FUT4 分子靶点信息

  • 分子名：FUT4, fucosyltransferase 4
  • 别称：
    • alpha (1,3) fucosyltransferase, myeloid-specific
    • alpha-(1,3)-fucosyltransferase
    • alpha-(1,3)-fucosyltransferase 4
    • CD15
    • ELAM ligand fucosyltransferase
    • ELAM-1 ligand fucosyltransferase
    • ELFT
    • FCT3A
    • FUC-TIV
    • fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    • fucosyltransferase IV
    • fucT-IV
    • FUTIV
    • galactoside 3-L-fucosyltransferase
    • Lewis X
    • LeX
    • SSEA-1
    • stage-specific embryonic antigen 1
  • 基因序列：NCBI_Gene: 2526
  • 蛋白序列：UniProtKB: P22083

人 Human FUT4靶点分子功能（预测）

Enables 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in oligosaccharide metabolic process and regulation of leukocyte cell-cell adhesion. Located in trans-Golgi network.

小鼠 Mouse Fut4 分子靶点信息

小鼠 Mouse Fut4 靶点分子功能（预测）

Predicted to enable 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in positive regulation of leukocyte tethering or rolling. Located in cell periphery and cell surface. Is expressed in several structures, including ear; embryo ectoderm; extraembryonic component; genitourinary system; and gut. Orthologous to human FUT4 (fucosyltransferase 4).

大鼠 Rat Fut4 分子靶点信息

  • 分子名：Fut4, fucosyltransferase 4
  • 别称：
    • alpha 1,3-fucosyltransferase Fuc-T (similar to mouse Fut4)
    • alpha 13-fucosyltransferase Fuc-T (similar to mouse Fut4)
    • alpha-(1,3)-fucosyltransferase
    • alpha-(1,3)-fucosyltransferase 4
    • fuc-TIV
    • fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
    • fucosyltransferase IV
    • Fuct
    • fucT-IV
    • galactoside 3-L-fucosyltransferase
  • 基因序列：NCBI_Gene: 60670
  • 蛋白序列：

大鼠 Rat Fut4 靶点分子功能（预测）

Enables alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation; oligosaccharide metabolic process; and positive regulation of leukocyte tethering or rolling. Predicted to be located in cell periphery; cell surface; and trans-Golgi network. Orthologous to human FUT4 (fucosyltransferase 4).

FUT4 分子产品列表

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