文章目录[隐藏]
CD5L 分子靶点信息概述
- 分子名:CD5L, CD5 molecule like
- 基因家族:Scavenger receptor cysteine rich domain containing
- 别名:Spalpha
- 曾用名:API6
- 全称:apoptosis inhibitor 6; CD5 antigen-like (scavenger receptor cysteine rich family); CD5 molecule-like
CD5L 分子靶点综述
CD5L(又称CD5抗原样蛋白)是一种可溶性蛋白,属于富含半胱氨酸的清道夫受体(SRCR)超家族B组,包含三个SRCR结构域。该蛋白是一种分泌型糖蛋白,由淋巴组织(脾脏、淋巴结、胸腺和骨髓)中的巨噬细胞表达。它能与髓系单核细胞和淋巴细胞结合,可能在先天性和适应性免疫系统的调控中发挥重要作用。
CD5L作为模式识别分子,既能结合革兰氏阳性菌的脂磷壁酸(LTA),又能结合革兰氏阴性菌的脂多糖(LPS)。其中,CD5L的SRCR结构域1同时保留了这两种结合活性。此外,研究表明CD5L似乎还具有抑制细胞凋亡的作用。
CD5L, CD5 molecule like 分子靶点种属信息
人 Human CD5L 分子靶点信息
- 分子名:CD5L, CD5 molecule like
- 别称:
- AIM
- API6
- apoptosis inhibitor 6
- apoptosis inhibitor expressed by macrophages
- apoptosis inhibitor of macrophage
- CD5 antigen-like
- CD5 antigen-like (scavenger receptor cysteine rich family)
- CD5 molecule-like
- CT-2
- hAIM
- igM-associated peptide
- PRO229
- SP-ALPHA
- Spalpha
- 基因序列:NCBI_Gene: 922
- 蛋白序列:UniProtKB: P43866
人 Human CD5L 靶点分子功能(预测)
Predicted to be involved in cellular defense response. Predicted to act upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface.
小鼠 Mouse Cd5l 分子靶点信息
- 分子名:Cd5l, CD5 antigen-like
- 别称:
- AAC-11
- AI047839
- AIM
- AIM/Spalpha
- Api6
- apoptosis inhibitor 6
- expressed sequence AI047839
- Pdp 1/6
- Sp-alpha
- 基因序列:NCBI_Gene: 11801
- 蛋白序列:
小鼠 Mouse Cd5l 靶点分子功能(预测)
Acts upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface and plasma membrane. Is expressed in several structures, including central nervous system; immune system; liver; retina; and testis. Orthologous to human CD5L (CD5 molecule like).
大鼠 Rat Cd5l 分子靶点信息
- 分子名:Cd5l, CD5 antigen-like
- 别称:
- CD5 antigen-like
- LOC310693
- MGC112716
- 基因序列:NCBI_Gene: 310693
- 蛋白序列:
大鼠 Rat Cd5l 靶点分子功能(预测)
Predicted to act upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Orthologous to human CD5L (CD5 molecule like).
CD5L 分子产品列表
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- EK2D5LEG
- 一步法ELISA试剂盒
EasyGo!™ Mouse CD5L One-Step ELISA Kit 检测试剂盒(酶联免疫吸附法)
- ¥2,190.00 – ¥3,650.00