文章目录[隐藏]
CCL16 分子靶点信息概述
- 分子名：CCL16, C-C motif chemokine ligand 16
- 基因家族：Chemokine ligands
- 别名：NCC-4; SCYL4; LEC; HCC-4; LMC; LCC-1; CKb12; Mtn-1
- 曾用名：SCYA16
- 全称：small inducible cytokine subfamily A (Cys-Cys), member 16; chemokine (C-C motif) ligand 16
CCL16 分子靶点综述
趋化因子CC配体16(CCL16)是CC趋化因子家族中的小分子细胞因子，也称为NCC-4、肝脏表达趋化因子(LEC)、以及淋巴细胞和单核细胞趋化因子(LMC)。这种趋化因子由肝脏、胸腺和脾脏表达，对单核细胞和淋巴细胞具有趋化性。在单核细胞中可以通过IL-10、IFN-γ和细菌脂多糖强烈诱导CCL16的细胞表达。此外，CCL16通过与细胞表面趋化因子受体 (如CCR1、CCR2、CCR5和CCR8 ) 相互作用而引发其对细胞的影响。该趋化因子会抑制骨髓前体细胞的快速增殖。
CCL16, C-C motif chemokine ligand 16 分子靶点种属信息
人 Human
人 Human CCL16 分子靶点信息
- 分子名：CCL16, C-C motif chemokine ligand 16
- 别称：
- C-C motif chemokine 16
- chemokine (C-C motif) ligand 16
- chemokine CC-4
- chemokine LEC
- CKb12
- HCC-4
- IL-10-inducible chemokine
- ILINCK
- LCC-1
- LEC
- liver CC chemokine-1
- liver-expressed chemokine
- LMC
- lymphocyte and monocyte chemoattractant
- MGC117051
- monotactin-1
- Mtn-1
- NCC-4
- NCC4
- new CC chemokine 4
- SCYA16
- SCYL4
- small inducible cytokine subfamily A (Cys-Cys), member 16
- small-inducible cytokine A16
- 基因序列：NCBI_Gene: 6360
- 蛋白序列：UniProtKB: O15467
人 Human CCL16靶点分子功能（预测）
Enables chemoattractant activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
