CCL16 分子靶点信息概述

  • 分子名:CCL16, C-C motif chemokine ligand 16
  • 基因家族:Chemokine ligands
  • 别名:NCC-4; SCYL4; LEC; HCC-4; LMC; LCC-1; CKb12; Mtn-1
  • 曾用名:SCYA16
  • 全称:small inducible cytokine subfamily A (Cys-Cys), member 16; chemokine (C-C motif) ligand 16

CCL16 分子靶点综述

趋化因子CC配体16(CCL16)是CC趋化因子家族中的小分子细胞因子,也称为NCC-4、肝脏表达趋化因子(LEC)、以及淋巴细胞和单核细胞趋化因子(LMC)。这种趋化因子由肝脏、胸腺和脾脏表达,对单核细胞和淋巴细胞具有趋化性。在单核细胞中可以通过IL-10、IFN-γ和细菌脂多糖强烈诱导CCL16的细胞表达。此外,CCL16通过与细胞表面趋化因子受体 (如CCR1、CCR2、CCR5和CCR8 ) 相互作用而引发其对细胞的影响。该趋化因子会抑制骨髓前体细胞的快速增殖。

CCL16, C-C motif chemokine ligand 16 分子靶点种属信息

人 Human

人 Human CCL16 分子靶点信息

  • 分子名:CCL16, C-C motif chemokine ligand 16
  • 别称:
    • C-C motif chemokine 16
    • chemokine (C-C motif) ligand 16
    • chemokine CC-4
    • chemokine LEC
    • CKb12
    • HCC-4
    • IL-10-inducible chemokine
    • ILINCK
    • LCC-1
    • LEC
    • liver CC chemokine-1
    • liver-expressed chemokine
    • LMC
    • lymphocyte and monocyte chemoattractant
    • MGC117051
    • monotactin-1
    • Mtn-1
    • NCC-4
    • NCC4
    • new CC chemokine 4
    • SCYA16
    • SCYL4
    • small inducible cytokine subfamily A (Cys-Cys), member 16
    • small-inducible cytokine A16
  • 基因序列:NCBI_Gene: 6360
  • 蛋白序列:UniProtKB: O15467

人 Human CCL16靶点分子功能(预测)

Enables chemoattractant activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in extracellular region. Predicted to be active in extracellular space.

CCL16 分子产品列表

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