CD79A 靶点信息

CD79A 分子靶点信息概述

  • 分子名：CD79A, CD79a molecule
  • 基因家族：CD molecules; V-set domain containing
  • 别名：MB-1
  • 曾用名：IGA
  • 全称：B-cell antigen receptor complex-associated protein alpha chain; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha

CD79A 分子靶点综述

CD79a 又称 mb-1，是一种 47kDa 膜糖蛋白，与 CD79b 结合形成异二聚体 B 细胞受体(BCR)。这种受体负责 B 细胞信号传导，导致激活、凋亡或过敏。从最早的B 细胞到浆细胞，CD79a 的表达一直存在。CD79 表达于 B 细胞肿瘤和一些非 B 细胞恶性肿瘤，如 AML。与其它可以在 B 细胞肿瘤细胞中表达的抗体不同，HM47 是识别 CD79a 的可靠抗体，因此是 B 细胞的良好标记。由于 CD79a 的几个变体存在，表位的确切位置可能略有不同。

CD79A, CD79a molecule 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human CD79A 分子靶点信息

  • 分子名：CD79A, CD79a molecule
  • 别称：
    • B-cell antigen receptor complex-associated protein alpha chain
    • CD79a antigen (immunoglobulin-associated alpha)
    • CD79a molecule, immunoglobulin-associated alpha
    • ig-alpha
    • IGA
    • MB-1
    • MB-1 membrane glycoprotein
    • membrane-bound immunoglobulin-associated protein
    • surface IgM-associated protein
  • 基因序列：NCBI_Gene: 973
  • 蛋白序列：UniProtKB: P11912

人 Human CD79A靶点分子功能（预测）

Enables identical protein binding activity. Predicted to be involved in B cell differentiation; B cell proliferation; and B cell receptor signaling pathway. Predicted to be located in membrane raft and multivesicular body. Predicted to be part of B cell receptor complex. Predicted to be active in external side of plasma membrane. Implicated in agammaglobulinemia.

小鼠 Mouse Cd79a 分子靶点信息

  • 分子名：Cd79a, CD79A antigen (immunoglobulin-associated alpha)
  • 别称：
    • aimmunoglobulin-associated alpha
    • CD79a antigen
    • Ig alpha
    • Ig-alpha
    • Iga
    • Igalpha
    • immunoglobulin-associated alpha
    • Ly-54
    • Ly54
    • lymphocyte antigen 54
    • mb-1
  • 基因序列：NCBI_Gene: 12518
  • 蛋白序列：

小鼠 Mouse Cd79a 靶点分子功能（预测）

Predicted to enable identical protein binding activity. Involved in B cell differentiation and B cell proliferation. Acts upstream of or within B cell receptor signaling pathway. Located in external side of plasma membrane; membrane raft; and multivesicular body. Part of B cell receptor complex. Is expressed in liver. Human ortholog(s) of this gene implicated in agammaglobulinemia. Orthologous to human CD79A (CD79a molecule).

大鼠 Rat Cd79a 分子靶点信息

  • 分子名：Cd79a, CD79a molecule
  • 别称：
    • -cell antigen receptor complex-associated protein alpha chain-like
    • B-cell antigen receptor complex-associated protein alpha chain
    • B-cell antigen receptor complex-associated protein alpha chain-like
    • CD79A antigen (immunoglobulin-associated alpha)
    • Cd79a molecule-like
    • Cd79a molecule, immunoglobulin-associated alpha
    • Cd79al
    • LOC100913063
  • 基因序列：NCBI_Gene: 100913063
  • 蛋白序列：

大鼠 Rat Cd79a 靶点分子功能（预测）

Predicted to enable identical protein binding activity. Predicted to be involved in B cell differentiation and B cell proliferation. Predicted to act upstream of or within B cell receptor signaling pathway. Predicted to be located in external side of plasma membrane; membrane raft; and multivesicular body. Predicted to be part of B cell receptor complex. Human ortholog(s) of this gene implicated in agammaglobulinemia. Orthologous to human CD79A (CD79a molecule).

CD79A 分子产品列表

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